| Name | estrogen receptors |
|---|---|
| Synonyms | ER; ERA; ER alpha; ERalpha; ESR; ESR 1; ESR1; ESRA… |
| Name | gamma-HCH |
|---|---|
| CAS | (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15253041 | Okubo T, Yokoyama Y, Kano K, Soya Y, Kano I: Estimation of estrogenic and antiestrogenic activities of selected pesticides by MCF-7 cell proliferation assay. Arch Environ Contam Toxicol. 2004 May;46(4):445-53. Estrogenic activities of 20 selected pesticides-which are used for agricultural production as insecticides, fungicides and herbicides-were examined by estrogen receptor (ER)-dependent MCF-7 cell proliferation assay. |
6(0,0,0,6) | Details |
| 11872169 | Lee HS, Miyauchi K, Nagata Y, Fukuda R, Sasagawa S, Endoh H, Kato S, Horiuchi H, Takagi M, Ohta A: Employment of the human estrogen receptor beta ligand-binding domain and co-activator SRC1 nuclear receptor-binding domain for the construction of a yeast two-hybrid detection system for endocrine disrupters. J Biochem. 2002 Mar;131(3):399-405. We constructed two-hybrid systems that co-express the Gal4p DNA binding domain/ligand-binding domain of human estrogen receptor (hER) alpha or beta and the Gal4p transactivation domain/nuclear receptor-binding domain of co-activator SRC1, TIF2, or AIB1 in Saccharomyces cerevisiae with a chromosome-integrated lacZ reporter gene under the control of Gal4p-binding sites. |
2(0,0,0,2) | Details |
| 9872718 | Celius T, Haugen TB, Grotmol T, Walther BT: A sensitive zonagenetic assay for rapid in vitro assessment of estrogenic potency of xenobiotics and mycotoxins. Environ Health Perspect. 1999 Jan;107(1):63-8. When cells were treated with xenoestrogens or mycotoxins in combination with an estrogen receptor inhibitor (ICI 182,780), the induction of both zr proteins and vitellogenin was inhibited in all cases. |
1(0,0,0,1) | Details |
| 17537412 | Maranghi F, Rescia M, Macri C, Di Consiglio E, De Angelis G, Testai E, Farini D, De Felici M, Lorenzetti S, Mantovani A: Lindane may modulate the female reproductive development through the interaction with ER-beta: an in vivo-in vitro approach. Chem Biol Interact. 2007 Aug 15;169(1):1-14. Epub 2007 Apr 22. Since both estrogen receptors (ER-alpha and -beta) have shown to be target for endocrine disruption, we investigated the role of gamma-HCH on the development of female reproductive system. |
1(0,0,0,1) | Details |
| 8783812 | Tiemann U, Schneider F, Tuchscherer A: Effects of organochlorine pesticides on DNA synthesis of cultured oviductal and uterine cells and on estrogen receptor of uterine tissue from heifers. Arch Toxicol. 1996;70(8):490-6. |
1(0,0,0,1) | Details |
| 7524197 | Laws SC, Carey SA, Hart DW, Cooper RL: Lindane does not alter the estrogen receptor or the -dependent induction of progesterone receptors in sexually immature or ovariectomized adult rats. Toxicology. 1994 Sep 6;92(1-3):127-42. It has been suggested that gamma-HCH may block the response of -dependent tissues to via an interaction with the estrogen receptor. |
1(0,0,0,1) | Details |