Protein Information

Name PC 3
Synonyms PC 3; secreted microprotein PC 3; secreted microprotein PC 3s

Compound Information

Name gamma-HCH
CAS (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane

Reference List

PubMed Abstract RScore(About this table)
14688026 Kalantzi OI, Hewitt R, Ford KJ, Cooper L, Alcock RE, Thomas GO, Morris JA, McMillan TJ, Jones KC, Martin FL: Low dose induction of micronuclei by lindane. . Carcinogenesis. 2004 Apr;25(4):613-22. Epub 2003 Dec 19.


Chromosomal damage in MCF-7 breast cells and PC-3 prostate cells was assessed using the cytokinesis block micronucleus assay.
3(0,0,0,3) Details
10696776 Schrader TJ, Cooke GM: Examination of selected food additives and organochlorine food contaminants for androgenic activity in vitro. Toxicol Sci. 2000 Feb;53(2):278-88.


In order to produce a reporter gene assay for androgenic chemicals, a constitutive expression vector coding for the human androgen receptor and a reporter construct containing the firefly luciferase coding sequence under transcriptional control of the androgen responsive MMTV promoter were cotransfected into the androgen-insensitive human PC-3 prostate carcinoma cell line and stable transfectants selected.
2(0,0,0,2) Details