| 11641424 |
Urwyler S, Mosbacher J, Lingenhoehl K, Heid J, Hofstetter K, Froestl W, Bettler B, Kaupmann K: Positive allosteric modulation of native and recombinant gamma-aminobutyric acid (B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol Pharmacol. 2001 Nov;60(5):963-71.
The compounds CGP7930 [2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol] and its close analog CGP13501 were identified as positive modulators of gamma-aminobutyric acid (B) (GABA (B)) receptor function.
The structurally related compounds propofol and malonoben are inactive. |
4(0,0,0,4) |
Details |