Protein Information

Name ACO1
Synonyms ACO 1; ACO1; Aconitase; Aconitase 1; Aconitase 1 variant; Aconitate hydratase; Citrate hydro lyase; Ferritin repressor protein…

Compound Information

Name 1-methylcyclopropene
CAS 1-methylcyclopropene

Reference List

PubMed Abstract RScore(About this table)
9426625 Bouquin T, Lasserre E, Pradier J, Pech JC, Balague C: Wound and ethylene induction of the ACC oxidase melon gene CM-ACO1 occurs via two direct and independent transduction pathways. Plant Mol Biol. 1997 Dec;35(6):1029-35.

The inhibitor of ethylene action, 1-methylcyclopropene (1-MCP), inhibited the accumulation of ethylene-induced CM-ACO1 mRNA transcripts, while wound-induced expression of the gene was not affected.
5(0,0,0,5) Details
9847103 Nakatsuka A, Murachi S, Okunishi H, Shiomi S, Nakano R, Kubo Y, Inaba A: Differential expression and internal feedback regulation of 1-aminocyclopropane-1-carboxylate synthase, 1-aminocyclopropane-1-carboxylate oxidase, and ethylene receptor genes in tomato fruit during development and ripening. Plant Physiol. 1998 Dec;118(4):1295-305.

These increases in mRNAs with ripening were prevented to a large extent by treatment with 1-methylcyclopropene (MCP), an ethylene action inhibitor.
The transcripts for LE-ACO1 and LE-ACO4 genes already existed in preclimacteric fruit and increased greatly when ripening commenced.
3(0,0,0,3) Details
18535299 Xue J, Li Y, Tan H, Yang F, Ma N, Gao J: Expression of ethylene biosynthetic and receptor genes in rose floral tissues during ethylene-enhanced flower opening. J Exp Bot. 2008;59(8):2161-9.


Ethylene production, as well as the expression of ethylene biosynthetic (Rh-ACS1-4 and Rh-ACO1) and receptor (Rh-ETR1-5) genes, was determined in five different floral tissues (sepals, petals, stamens, gynoecia, and receptacles) of cut rose (Rosa hybrida cv.
2(0,0,0,2) Details
17185740 Inaba A, Liu X, Yokotani N, Yamane M, Lu WJ, Nakano R, Kubo Y: Differential feedback regulation of ethylene biosynthesis in pulp and peel tissues of banana fruit. J Exp Bot. 2007;58(5):1047-57. Epub 2006 Dec 21.

Grand Nain] fruit was investigated in an attempt to clarify the opposite effect of 1-methylcyclopropene (1-MCP), an ethylene action inhibitor, before and after the onset of ripening. 1-MCP pre-treatment completely prevented the ripening-induced effect of propylene in pre-climacteric banana fruit, whereas treatment after the onset of ripening stimulated ethylene production.
In contrast, in the peel of ripening fruit, 1-MCP prevented the increase in ethylene production and subsequently the ripening process by reduction of the increase in MA-ACS1 and MA-ACO1 transcripts and of ACC synthase and ACC oxidase activities.
1(0,0,0,1) Details
16844735 Ma N, Tan H, Liu X, Xue J, Li Y, Gao J: Transcriptional regulation of ethylene receptor and CTR genes involved in ethylene-induced flower opening in cut rose (Rosa hybrida) cv. J Exp Bot. 2006;57(11):2763-73. Epub 2006 Jul 14.

However, although ethylene hastened the process of flower opening, 1-MCP (1-methylcyclopropene), an ethylene action inhibitor, impeded it.
Of the four ethylene biosynthetic genes tested, Rh-ACS1 and Rh-ACS2 were undetectable; Rh-ACS3 and Rh-ACO1 expression was enhanced by ethylene slightly and greatly, respectively.
1(0,0,0,1) Details
16881689 Zheng QL, Nakatsuka A, Itamura H: Involvement of negative feedback regulation in wound-induced ethylene synthesis in 'Saijo' persimmon. J Agric Food Chem. 2006 Aug 9;54(16):5875-9.

We found that wound-induced ethylene biosynthesis is subjected to negative feedback regulation in mature 'Saijo' persimmon fruit since ethylene production was enhanced by 1-methylcyclopropene (1-MCP) (an inhibitor of ethylene perception) pretreatment, which was approximately 1.8 fold of that in control tissues (without 1-MCP pretreatment).
Out of accord with DK-ACO1 gene expression, ACC oxidase activity was enhanced 48 h after wounding in 1-MCP pretreated tissues, reaching a peak 1.5-fold higher than that in control tissues at 60 h.
1(0,0,0,1) Details
16889975 Owino WO, Manabe Y, Mathooko FM, Kubo Y, Inaba A: Regulatory mechanisms of ethylene biosynthesis in response to various stimuli during maturation and ripening in fig fruit (Ficus carica L.). Plant Physiol Biochem. 2006 May-Jun;44(5-6):335-42. Epub 2006 Jul 7.

The ethylene production in response to olive oil, auxin, and propylene treatments and during ripening were all induced by 1-methylcyclopropene (1-MCP) and inhibited by propylene indicating a negative feedback regulation mechanism.
Three 1-aminocyclopropane-1-carboxylic acid (ACC) synthase genes (Fc-ACS1, Fc-ACS2 and Fc-ACS3) and one ACC oxidase gene (Fc-ACO1) were isolated and their expression patterns in response to either oil, propylene or auxin treatment in figs determined.
1(0,0,0,1) Details
12529535 Nakano R, Ogura E, Kubo Y, Inaba A: Ethylene biosynthesis in detached young persimmon fruit is initiated in calyx and modulated by water loss from the fruit. Plant Physiol. 2003 Jan;131(1):276-86.

To investigate ethylene induction mechanisms in detached young persimmon fruit, we cloned three cDNAs encoding 1-aminocyclopropane-1-carboxylic acid (ACC) synthase (DK-ACS1, 2, and -3) and two encoding ACC oxidase (DK-ACO1 and -2) genes involved in ethylene biosynthesis, and we analyzed their expression in various fruit tissues.
In all tissues except the calyx, treatment with 1-methylcyclopropene, an inhibitor of ethylene action, suppressed ethylene production and ethylene biosynthesis-related gene expression.
1(0,0,0,1) Details