| Name | 5 HT1A |
|---|---|
| Synonyms | 5 HT 1A; serotonin receptor; 5 HT1A; 5 hydroxytryptamine (serotonin) receptor 1A; 5 hydroxytryptamine 1A receptor; 5HT1A; ADRB2RL1; ADRBRL 1… |
| Name | ACC |
|---|---|
| CAS | 1-aminocyclopropanecarboxylic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18585397 | Ohno Y, Shimizu S, Imaki J, Ishihara S, Sofue N, Sasa M, Kawai Y: Anticataleptic 8-OH-DPAT preferentially counteracts with haloperidol-induced Fos expression in the dorsolateral striatum and the core region of the nucleus accumbens. Neuropharmacology. 2008 Oct;55(5):717-23. Epub 2008 Jun 10. These results suggest that 8-OH-DPAT alleviates antipsychotic-associated extrapyramidal motor disorders by stimulating the postsynaptic 5-HT (1A) receptors, which specifically counteracts the D (2) receptor blocking actions of antipsychotics in the dlST and AcC. |
32(0,1,1,2) | Details |
| 19352073 | Ohno Y, Shimizu S, Imaki J: Effects of tandospirone, a 5-HT1A agonistic anxiolytic agent, on haloperidol-induced catalepsy and forebrain Fos expression in mice. J Pharmacol Sci. 2009 Apr;109(4):593-9. Epub 2009 Apr 7. Haloperidol (0.5 mg/kg, i.p.) markedly increased the catalepsy time and enhanced Fos expression in the shell (AcS) and core (AcC) regions of the nucleus accumbens, the dorsolateral striatum (dlST), and the lateral septal nucleus (LSN). |
4(0,0,0,4) | Details |
| 18583156 | Frey BN, Rosa-Neto P, Lubarsky S, Diksic M: Correlation between synthesis and 5-HT1A receptor binding in the living human brain: a combined alpha-[11C] MT and [18F] MPPF positron emission tomography study. Neuroimage. 2008 Aug 15;42(2):850-7. Epub 2008 May 17. |
3(0,0,0,3) | Details |
| 19102816 | Law AJ, Pei Q, Feldon J, Pryce CR, Harrison PJ: Gene expression in the anterior cingulate cortex and amygdala of adolescent marmoset monkeys following parental separations in infancy. Int J Neuropsychopharmacol. 2009 Jul;12(6):761-72. Epub 2008 Dec 23. Here we report the long-term effect (in adolescence) of this intervention on the expression of synaptophysin, GAP-43, VGluT1, VGAT, MAP-2, spinophilin, and 5-HT1A and 5-HT2A receptors, in the anterior cingulate cortex (ACC; supragenual and subgenual areas) and amygdala (lateral, basal and central nuclei). |
2(0,0,0,2) | Details |
| 18404667 | Palomero-Gallagher N, Mohlberg H, Zilles K, Vogt B: Cytology and receptor architecture of human anterior cingulate cortex. J Comp Neurol. 2008 Jun 20;508(6):906-26. Subgenual ACC has significantly higher (A), (B), benzodiazepine (BZ), alpha (1), and 5-HT (1A) densities than pACC. |
1(0,0,0,1) | Details |
| 19358877 | Savitz JB, Drevets WC: Imaging phenotypes of major depressive disorder: genetic correlates. Neuroscience. 2009 Nov 24;164(1):300-30. Epub 2009 Apr 7. Concerning neuroreceptor PET imaging, decreased 5-HT (1A) binding potential in the raphe, medial temporal lobe, and medial prefrontal cortex (mPFC) has been strongly associated with MDD, and may be impacted by a functional single nucleotide polymorphism in the promoter region of the 5-HT (1A) gene (HTR1A: -1019 C/G; rs6295). |
1(0,0,0,1) | Details |
| 19034899 | Palomero-Gallagher N, Vogt BA, Schleicher A, Mayberg HS, Zilles K: Receptor architecture of human cingulate cortex: evaluation of the four-region neurobiological model. Hum Brain Mapp. 2009 Aug;30(8):2336-55. The ACC has highest AMPA, kainate, alpha (2), 5-HT (1A), and D (1) but lowest (A) densities. |
1(0,0,0,1) | Details |