Protein Information

Name PCNA
Synonyms Cyclin; DNA polymerase delta auxillary protein; PCNA; Proliferating cell nuclear antigen; DNA polymerase delta auxillary proteins; Proliferating cell nuclear antigens

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
18366613 Yang JY, Yang MQ, Luo Z, Ma Y, Li J, Deng Y, Huang X: A hybrid machine learning-based method for classifying the Cushing's Syndrome with comorbid adrenocortical lesions. BMC Genomics. 2008;9 Suppl 1:S23.


It follows from a comprehensive statistical analysis that a number of antigens such as hTERT, PCNA and Ki-67 can be considered as cancer markers, while another set of antigens such as P27KIP1 and FHIT are possible markers for normal tissue.
3(0,0,0,3) Details
19931513 Huang QM, Akashi T, Masuda Y, Kamiya K, Takahashi T, Suzuki M: Roles of POLD4, smallest subunit of DNA polymerase delta, in nuclear structures and genomic stability of human cells. Biochem Biophys Res Commun. 2010 Jan 1;391(1):542-6. Epub 2009 Nov 24.


We investigated pol delta activities in vitro and found that it was less active in the absence of POLD4, irrespective of the presence of the accessory protein PCNA. shRNA-mediated reduction of POLD4 resulted in a marked decrease in colony formation activity by Calu6, ACC-LC-319, and PC-10 cells.
1(0,0,0,1) Details
19886254 Otrocka-Domagala I, Rotkiewicz T, Podbielski M, Wisniewska A, Drzewiecka A: Effect of butaphosphane and cyanocobalamin on regeneration of muscle fibres in pigs. Pol J Vet Sci. 2009;12(3):329-38.

Preparations obtained from muscle specimens were stained with HE, PAS method acc. to McManus, HBFP, Feulgen, and Unna methods.
The presence of vimentin, desmin and PCNA was detected immunohistochemically in sections prepared with a paraffin method.
1(0,0,0,1) Details