Protein Information

Name IL 12 (protein family or complex)
Synonyms Cytotoxic lymphocyte maturation factor; Cytotoxic lymphocyte maturation factors; IL 12; IL12; Natural killer cell stimulatory factor; Natural killer cell stimulatory factors

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
18972297 Movahedi M, Mahdaviani SA, Rezaei N, Moradi B, Dorkhosh S, Amirzargar AA: IL-10, TGF-beta, IL-2, IL-12, and IFN-gamma cytokine gene polymorphisms in asthma. J Asthma. 2008 Nov;45(9):790-4.

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19470040 Javor J, Chmurova N, Parnicka Z, Ferencik S, Grosse-Wilde H, Buc M, Svecova D: TNF-alpha and IL-10 gene polymorphisms show a weak association with pemphigus vulgaris in the Slovak population. J Eur Acad Dermatol Venereol. 2010 Jan;24(1):65-8. Epub 2009 Apr 8.


OBJECTIVE: The aim of our case-control study was to investigate whether some of 22 single nucleotide polymorphisms (SNPs) in 13 cytokine genes (IL-1alpha, IL-1beta, IL-1RI, IL-1Ra, IL-4Ralpha, IL-12, IFN-gamma, TGF-beta1, TNF-alpha, IL-2, IL-4, IL-6 and IL-10) are associated with pemphigus vulgaris in the Slovak population.
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18457043 Pogoda TV, Marsheva OV, Kostin PA, Maksimov VN, Kulikov IV, Openko TG, Simonova GI, Voyevoda MI, Generozov EV, Govorun VM: Association of haplotypes of interleukin-10 gene with the risk of cancer. Bull Exp Biol Med. 2007 Sep;144(3):385-9.


Polymorphisms of promotor region of IL-8, IL-10, and IL-12 genes were analyzed in cancer patients and subjects without history of cancer.
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