Protein Information

Name 1 aminocyclopropane 1 carboxylate synthase
Synonyms 1 aminocyclopropane 1 carboxylate synthase; ACS; ACC synthase; PHACS; ACC synthases

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
17525098 Okazaki S, Sugawara M, Yuhashi K, Minamisawa K: Rhizobitoxine-induced chlorosis occurs in coincidence with methionine deficiency in soybeans. Ann Bot. 2007 Jul;100(1):55-9. Epub 2007 May 24.


BACKGROUND AND AIMS: Rhizobitoxine, produced by the legume symbiont Bradyrhizobium elkanii, inhibits cystathionine-beta-lyase (EC 4.4.1.8) in methionine biosynthesis and 1-aminocyclopropane-1-carboxylate synthase (ACC) in ethylene biosynthesis.
1(0,0,0,1) Details
17922660 Yao Y, Du Y, Jiang L, Liu JY: Interaction between ACC synthase 1 and 14-3-3 proteins in rice: a new insight. Biochemistry. 2007 Sep;72(9):1003-7.

1(0,0,0,1) Details
18367517 Salman-Minkov A, Levi A, Wolf S, Trebitsh T: ACC synthase genes are polymorphic in watermelon (Citrullus spp.) and differentially expressed in flowers and in response to auxin and gibberellin. Plant Cell Physiol. 2008 May;49(5):740-50. Epub 2008 Mar 26.


In cucumber, the rate-limiting enzyme of ethylene biosynthesis, 1-aminocyclopropane-1-carboxylate (ACC) synthase (ACS), regulates unisexual flower development.
1(0,0,0,1) Details
18194424 Casteel CL, O'Neill BF, Zavala JA, Bilgin DD, Berenbaum MR, Delucia EH: Transcriptional profiling reveals elevated CO2 and elevated O3 alter resistance of soybean (Glycine max) to Japanese beetles (Popillia japonica). Plant Cell Environ. 2008 Apr;31(4):419-34. Epub 2008 Jan 9.


Constitutive levels and the induction by herbivory of key transcripts associated with defence and hormone signalling were down-regulated under elevated CO2; 1-aminocyclopropane-1-carboxylate (ACC) synthase, lipoxygenase (LOX), allene oxide synthase (AOS), allene oxide cyclase (AOC), chalcone synthase (CHS), polyphenol oxidase (PPO) and cysteine protease inhibitor (CystPI) were lower in abundance compared with levels under ambient conditions.
1(0,0,0,1) Details
19704705 Patrick B, Antonin L, Servane LL, Deleu C, Le Deunff E: Ethylene modifies architecture of root system in response to stomatal opening and water allocation changes between root and shoot. Plant Signal Behav. 2009 Jan;4(1):44-6.

Ethylene plays a key role in the elongation of exploratory and root hair systems in plants, as demonstrated by pharmacological modulation of the activity of ethylene biosynthesis enzymes: ACC synthase (ACS) and ACC oxidase (ACO).
31(0,1,1,1) Details
17927914 Wang X, Zhang Y, Zhang J, Cheng C, Guo X: Molecular characterization of a transient expression gene encoding for 1-aminocyclopropane-1-carboxylate synthase in cotton (Gossypium hirsutum L.). J Biochem Mol Biol. 2007 Sep 30;40(5):791-800.

2(0,0,0,2) Details
18328643 Barnes JR, Lorenz WW, Dean JF: Characterization of a 1-aminocyclopropane-1-carboxylate synthase gene from loblolly pine (Pinus taeda L.). Gene. 2008 Apr 30;413(1-2):18-31. Epub 2008 Jan 24.

2(0,0,0,2) Details
19752216 Tsuchisaka A, Yu G, Jin H, Alonso JM, Ecker JR, Zhang X, Gao S, Theologis A: A combinatorial interplay among the 1-aminocyclopropane-1-carboxylate isoforms regulates ethylene biosynthesis in Arabidopsis thaliana. Genetics. 2009 Nov;183(3):979-1003. Epub 2009 Sep 14.


The key enzyme in the two-step biosynthetic pathway of ethylene is 1-aminocyclopropane-1-carboxylate synthase (ACS), which catalyzes the conversion of S-adenosylmethionine (AdoMet) to ACC, the precursor of ethylene.
1(0,0,0,1) Details