Name | caspase 3 |
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Synonyms | Apopain; CASP 3; CASP3; CPP 32; CPP32; CPP32B; Caspase 3; Caspase 3 precursor… |
Name | IAA |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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20225657 | Jeong YM, Oh MH, Kim SY, Li H, Yun HY, Baek KJ, Kwon NS, Kim WY, Kim DS: urinary bladder carcinoma cells. Pharmazie. 2010 Feb;65(2):122-6. We further investigated the IAA/HRP-mediated apoptotic pathways and showed that IAA/HRP induces caspase-8 and caspase-9 activation, which results in caspase-3 activation and poly (ADP- polymerase (PARP) cleavage. |
/horseradish peroxidase induces apoptosis in TCCSUP human 1(0,0,0,1) | Details |
17142972 | Kim DS, Kim SY, Jeong YM, Jeon SE, Kim MK, Kwon SB, Na JI, Park KC: Light-activated induces apoptosis in g361 human melanoma cells. Biol Pharm Bull. 2006 Dec;29(12):2404-9. We further investigated IAAUVB-mediated apoptotic pathways, and found that IAAUVB causes caspase-8, Bid, caspase-3 activation, and poly (ADP- polymerase (PARP) cleavage. |
1(0,0,0,1) | Details |
12244574 | Greco O, Dachs GU, Tozer GM, Kanthou C: Mechanisms of cytotoxicity induced by horseradish peroxidase/ In the present work, some of the molecular and morphological features of the cells treated with HRP/IAA gene therapy were analysed. |
gene therapy. J Cell Biochem. 2002;87(2):221-32.0(0,0,0,0) | Details |
11833936 | Abdo MA, Richards A, Atiya N, Singh B, Parkinson S, Hisheh S, Dharmarajan AM: Inhibitors of caspase homologues suppress an apoptotic phenotype in cultured rabbit corpora lutea. Reprod Fertil Dev. 2001;13(5-6):395-403. The final component of the study was to examine caspase-3 protein expression. |
3(0,0,0,3) | Details |
19721241 | Park KC, Kim SY, Kim DS: Experimental photodynamic therapy for liver cancer cell-implanted nude mice by an and intense pulsed light combination. Biol Pharm Bull. 2009 Sep;32(9):1609-13. Then, tissue was taken for terminal deoxynucleotidyl transferase-mediated nick-end labeling (TUNEL) assay and immunohistochemical staining for p53, caspase-3, and proliferating cell nuclear antigen (PCNA). |
2(0,0,0,2) | Details |
18164246 | d'Anglemont de Tassigny A, Berdeaux A, Souktani R, Henry P, Ghaleh B: The volume-sensitive chloride channel inhibitors prevent both contractile dysfunction and apoptosis induced by doxorubicin through PI3kinase, Akt and Erk 1/2. Eur J Heart Fail. 2008 Jan;10(1):39-46. Doxorubicin induced increases in both annexin V labelling and caspase-3 activity and decreases in cell volume. |
2(0,0,0,2) | Details |
14607278 | Kim DS, Jeon SE, Park KC: Oxidation of by horseradish peroxidase induces apoptosis in G361 human melanoma cells. Cell Signal. 2004 Jan;16(1):81-8. We further investigated the IAA/HRP-mediated apoptotic pathways, and found that IAA/HRP activates caspase-8 and caspase-9, leading to caspase-3 activation and poly (ADP- polymerase (PARP) cleavage. |
1(0,0,0,1) | Details |
15855049 | Dhar-Mascareno M, Carcamo JM, Golde DW: Hypoxia-reoxygenation-induced mitochondrial damage and apoptosis in human endothelial cells are inhibited by Free Radic Biol Med. 2005 May 15;38(10):1311-22. Since is a potent antioxidant and quenches ROS, we investigated the role of intracellular (iAA) in endothelial cells undergoing hypoxia-reperfusion. Intracellular AA also prevents loss of mitochondrial membrane potential and the release of cytochrome C and activation of caspase-9 and caspase-3 during H-R. |
1(0,0,0,1) | Details |
16880616 | Kim DS, Kim SY, Jeong YM, Jeon SE, Kim MK, Kwon SB, Park KC: cell surface CD95 (Fas/APO-1) expression. Biol Pharm Bull. 2006 Aug;29(8):1625-9. In addition, the IAA/HRP-induced activations of CD95 downstream molecules, i.e., caspase-8, Bid, and caspase-3, were also inhibited by catalase. |
/horseradish peroxidase-induced apoptosis involves 1(0,0,0,1) | Details |
15482374 | d'Anglemont de Tassigny A, Souktani R, Henry P, Ghaleh B, Berdeaux A: Volume-sensitive mediate doxorubicin-induced apoptosis through apoptotic volume decrease in cardiomyocytes. Fundam Clin Pharmacol. 2004 Oct;18(5):531-8. AVD as well as increases in the early markers of apoptosis, annexin V labeling and caspase-3 activity. |
channels (ICl,vol) 1(0,0,0,1) | Details |
16460736 | Kim DS, Jeon SE, Jeong YM, Kim SY, Kwon SB, Park KC: On further investigating the IAA/HRP-mediated apoptotic pathway, we found that the IAA/HRP reaction leads to caspase-3 activation and poly (ADP- polymerase (PARP) cleavage, which was also blocked by catalase. |
peroxide is a mediator of /horseradish peroxidase-induced apoptosis. FEBS Lett. 2006 Feb 20;580(5):1439-46. Epub 2006 Jan 31.1(0,0,0,1) | Details |