Protein Information

Name Acetylcholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

Name IAA
CAS

Reference List

PubMed Abstract RScore(About this table)
12162322 Momonoki YS, Hineno C, Noguchi K: Acetylcholine as a signaling system to environmental stimuli in plants. Plant Prod Sci. 1998;1(2):83-8.


Asymmetric distribution of acetylcholinesterase (AChE) activity has previously been demonstrated to occur in the lower side of the gravity-stimulated maize shoot.
5(0,0,0,5) Details
19414266 Suna H, Arai M, Tsubotani Y, Hayashi A, Setiawan A, Kobayashi M: Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death. Bioorg Med Chem. 2009 Jun 1;17(11):3968-72. Epub 2009 Apr 18.

Compounds 1 and 2 showed neuroprotective effect against iodoacetic acid (IAA)-induced cell death at 10 microM concentration in mouse HT22 hippocampal neuronal cells.
Moreover, 1 induced neurite outgrowth against mouse neuroblastoma Neuro 2A cells with increase of acetylcholinesterase (AChE) activity, which is a marker of neuronal differentiation.
1(0,0,0,1) Details
18383919 Siatka T, Kasparova M: Effects of auxins on growth and scopoletin accumulation in cell suspension cultures of Angelica archangelica L. Ceska Slov Farm. 2008 Jan;57(1):17-20.


Scopoletin is a coumarin possessing many interesting biological effects, e.g., spasmolytic, anti-inflammatory, antimutagenic, antioxidant, antifungal, apoptosis-inducing, antiproliferative, acetylcholinesterase-inhibitory, and hypouricemic activities.
1(0,0,0,1) Details