Name | CTLA 4 |
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Synonyms | CD152; GSE; CELIAC 3; CELIAC3; CTLA4; CD152 antigen; CTLA 4; Cytotoxic T lymphocyte antigen 4… |
Name | IAA |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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9353155 | Van der Auwera BJ, Vandewalle CL, Schuit FC, Winnock F, De Leeuw IH, Van Imschoot S, Lamberigts G, Gorus FK: CTLA-4 gene polymorphism confers susceptibility to insulin-dependent diabetes mellitus (IDDM) independently from age and from other genetic or immune disease markers. Clin Exp Immunol. 1997 Oct;110(1):98-103. |
4(0,0,0,4) | Details |
10916559 | Krokowski M, Abel M, Teodorczyk A, Szadkowska A, Pyrzak B, Rymkiewicz-Kluczynska B, Bodalski J: Type 1 diabetes and prediabetic state in a monozygotic triplet. Acta Genet Med Gemellol. 1998;47(3-4):171-6. Genetic predisposition for IDDM is connected with HLA, CTLA-4 and insulin gene region. |
3(0,0,0,3) | Details |
16025255 | Hermann R, Laine AP, Veijola R, Vahlberg T, Simell S, Lahde J, Simell O, Knip M, Ilonen J: The effect of HLA class II, insulin and CTLA4 gene regions on the development of humoral beta cell autoimmunity. Diabetologia. 2005 Sep;48(9):1766-75. Epub 2005 Jul 16. |
3(0,0,0,3) | Details |
16442659 | Holmberg H, Vaarala O, Sadauskaite-Kuehne V, Ilonen J, Padaiga Z, Ludvigsson J: Higher prevalence of autoantibodies to insulin and GAD65 in Swedish compared to Lithuanian children with type 1 diabetes. Diabetes Res Clin Pract. 2006 Jun;72(3):308-14. Epub 2006 Jan 26. We analyzed autoantibodies to insulin (IAA), glutamic acid decarboxylase (GADA) and the protein tyrosine phosphatase like IA-2 (IA-2A) as well as risk-associated polymorphisms of HLA, insulin and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) genes. |
2(0,0,0,2) | Details |
16614815 | Hermann R, Lipponen K, Kiviniemi M, Kakko T, Veijola R, Simell O, Knip M, Ilonen J: Lymphoid phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes. Diabetologia. 2006 Jun;49(6):1198-208. Epub 2006 Apr 14. All subjects were typed for HLA DR-DQ, insulin gene (INS), CTLA4 and PTPN22 C1858T polymorphisms. |
1(0,0,0,1) | Details |
19473815 | Lempainen J, Vaarala O, Makela M, Veijola R, Simell O, Knip M, Hermann R, Ilonen J: Interplay between PTPN22 C1858T polymorphism and cow's milk formula exposure in type 1 diabetes. J Autoimmun. 2009 Sep;33(2):155-64. Epub 2009 May 26. We studied the effect of the INS -23A/T, PTPN22 1858C/T, and CTLA-4 +49A/G polymorphisms on the emergence of T1D-associated autoimmunity in children exposed to cow's milk (CM) based formula during early or late infancy. |
1(0,0,0,1) | Details |