Name | ubiquitin protein ligase |
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Synonyms | E2(25K); Ubiquitin carrier protein; Ubiquitin protein ligase; E2 25K; HIP 2; HIP2; HYPG; Huntingtin interacting protein 2… |
Name | IAA |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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12839993 | Hellmann H, Hobbie L, Chapman A, Dharmasiri S, Dharmasiri N, del Pozo C, Reinhardt D, Estelle M: Arabidopsis AXR6 encodes CUL1 implicating SCF E3 ligases in auxin regulation of embryogenesis. EMBO J. 2003 Jul 1;22(13):3314-25. One of the effects of auxin is to stimulate degradation of the Aux/IAA auxin response proteins through the action of the ubiquitin protein ligase SCF (TIR1). |
1(0,0,0,1) | Details |
15546359 | Yang X, Lee S, So JH, Dharmasiri S, Dharmasiri N, Ge L, Jensen C, Hangarter R, Hobbie L, Estelle M: The IAA1 protein is encoded by AXR5 and is a substrate of SCF (TIR1). Plant J. 2004 Dec;40(5):772-82. TIR1 is part of a ubiquitin protein ligase required for degradation of Aux/IAA proteins. |
1(0,0,0,1) | Details |
12226665 | Xie Q, Guo HS, Dallman G, Fang S, Weissman AM, Chua NH: SINAT5 promotes ubiquitin-related degradation of NAC1 to attenuate auxin signals. Nature. 2002 Sep 12;419(6903):167-70. Here we show that SINAT5, an Arabidopsis homologue of the RING-finger Drosophila protein SINA, has ubiquitin protein ligase activity and can ubiquitinate NAC1. |
1(0,0,0,1) | Details |
12782725 | Gray WM, Muskett PR, Chuang HW, Parker JE: Arabidopsis SGT1b is required for SCF (TIR1)-mediated auxin response. Plant Cell. 2003 Jun;15(6):1310-9. This complex functions as a ubiquitin protein ligase that targets members of the auxin/ (Aux/IAA) family of transcriptional regulators for ubiquitin-mediated degradation in response to auxin. |
1(0,0,0,1) | Details |
11709180 | Rogg LE, Bartel B: Auxin signaling: derepression through regulated proteolysis. Dev Cell. 2001 Nov;1(5):595-604. Aux/IAA proteins are unstable, and their degradation is triggered by a ubiquitin-protein ligase that is regulated by modification with a ubiquitin-related protein. |
1(0,0,0,1) | Details |
16488128 | Parry G, Estelle M: Auxin receptors: a new role for F-box proteins. Curr Opin Cell Biol. 2006 Apr;18(2):152-6. Epub 2006 Feb 17. Genetic and biochemical studies have shown that this degradation is dependent on a ubiquitin protein ligase called SCF (TIR1). |
1(0,0,0,1) | Details |
15917797 | Dharmasiri N, Dharmasiri S, Estelle M: The F-box protein TIR1 is an auxin receptor. . Nature. 2005 May 26;435(7041):441-5. Recent studies indicate that auxin acts by promoting the degradation of the Aux/IAA transcriptional repressors through the action of the ubiquitin protein ligase SCF (TIR1). |
1(0,0,0,1) | Details |