| Name | Sonic hedgehog |
|---|---|
| Synonyms | HHG 1; HHG1; HLP 3; HLP3; HPE 3; HPE3; SHH; SMMCI… |
| Name | IBA |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12915230 | Fukuda K, Kameda T, Saitoh K, Iba H, Yasugi S: Down-regulation of endodermal Shh is required for gland formation in chicken stomach. Mech Dev. 2003 Jul;120(7):801-9. Sonic hedgehog is expressed uniformly in the proventricular epithelium before gland formation, but its expression ceases in gland cells. |
2(0,0,0,2) | Details |
| 10751185 | Sukegawa A, Narita T, Kameda T, Saitoh K, Nohno T, Iba H, Yasugi S, Fukuda K: The concentric structure of the developing gut is regulated by Sonic hedgehog derived from endodermal epithelium. Development. 2000 May;127(9):1971-80. |
2(0,0,0,2) | Details |
| 11965540 | Koike C, Mizutani T, Ito T, Shimizu Y, Yamamichi N, Kameda T, Michimukai E, Kitamura N, Okamoto T, Iba H: Introduction of wild-type patched gene suppresses the oncogenic potential of human squamous cell carcinoma cell lines including A431. Oncogene. 2002 Apr 18;21(17):2670-8. When SSC cells were transduced with Ptc virus, colony forming activity in soft agar was drastically reduced and these cells recovered anchorage independent growth when Sonic hedgehog (Shh), the ligand of Patched (Ptc), was added into the soft agar culture. |
1(0,0,0,1) | Details |
| 9569029 | Matsumoto K, Saitoh K, Koike C, Narita T, Yasugi S, Iba H: Differential expression of fos and jun family members in the developing chicken gastrointestinal tract. Oncogene. 1998 Mar 26;16(12):1611-6. Similar expression patterns to those of fra-2 and junD were established from earlier stages by Sonic hedgehog gene and the Indian hedgehog gene, respectively, both of which are important in forming the inductive network between epithelium and mesenchyme of the digestive tract. |
1(0,0,0,1) | Details |
| 12584568 | Shimizu Y, Yamamichi N, Saitoh K, Watanabe A, Ito T, Yamamichi-Nishina M, Mizutani M, Yahagi N, Suzuki T, Sasakawa C, Yasugi S, Ichinose M, Iba H: Kinetics of v-src-induced epithelial-mesenchymal transition in developing glandular stomach. Oncogene. 2003 Feb 13;22(6):884-93. In response to the transient expression of v-Src or a constitutive active mutant of MEK, we observed immediate downregulation of the Sonic hedgehog gene and subsequent elimination of E-cadherine expression in migrating cells, suggesting the involvement of MAP kinase signaling pathway in these processes. v-src-expressing cells that were retained in the epithelium underwent apoptosis (anoikis) and detached from the culture. |
1(0,0,0,1) | Details |