Protein Information

Name G alpha o
Synonyms G ALPHA o; GNAO; GNAO 1; GNAO1; Guanine nucleotide binding protein G(o) subunit alpha 1; Guanine nucleotide binding protein G(o) subunit alpha 2; Guanine nucleotide binding protein G(o) subunit alpha 1s; Guanine nucleotide binding protein G(o) subunit alpha 2s

Compound Information

Name IBA
CAS

Reference List

PubMed Abstract RScore(About this table)
8308719 Campbell V, Berrow N, Dolphin AC: GABAB receptor modulation of Ca2+ currents in rat sensory neurones by the G protein G (0): antisense oligonucleotide studies. J Physiol. 1993 Oct;470:1-11.

Following G alpha o oligonucleotide injection, (-)-baclofen inhibited IBa by 21.0 +/- 3.2% (n = 19). 3.
90(1,1,2,5) Details
8309795 Menon-Johansson AS, Berrow N, Dolphin AC: G (o) transduces GABAB-receptor modulation of N-type calcium channels in cultured dorsal root ganglion neurons. Pflugers Arch. 1993 Nov;425(3-4):335-43.

Replating DRGs in the presence of anti-G (o) antiserum, raised against the C-terminal decapeptide of the G alpha o subunit, reduced (-)-baclofen inhibition of the HVA IBa, whereas replating DRGs in the presence of the anti-Gi antiserum did not.
85(1,1,1,5) Details