| Name | enkephalin |
|---|---|
| Synonyms | Met enkephalin; enkephalin; M enkephalin |
| Name | IBA |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10602337 | Connor M, Borgland SL, Christie MJ: Continued morphine modulation of calcium channel currents in acutely isolated locus coeruleus neurons from morphine-dependent rats. Br J Pharmacol. 1999 Dec;128(7):1561-9. In spontaneously withdrawn LC neurons from morphine-dependent rats, met-enkephalin (pD2 7.1, maximum inhibition 49%) and morphine (pD2 6.5, maximum inhibition 33%), inhibited IBa in all cells. |
194(2,3,3,4) | Details |
| 10323586 | Connor M, Schuller A, Pintar JE, Christie MJ: Mu-opioid receptor modulation of calcium channel current in periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR-1. Br J Pharmacol. 1999 Apr;126(7):1553-8. The endogenous opioid agonist -enkephalin (met-enkephalin, pEC50 6.8, maximum inhibition 40%), the putative endogenous mu-opioid agonist (pEC50 6.2, maximum inhibition 35%) and the mu-opioid selective agonist DAMGO (Tyr-D--Gly-N-Me--Gly-ol enkephalin, pEC50 6.9, maximum inhibition 40%) inhibited IBa in 70% of mouse PAG neurons. |
112(1,2,2,2) | Details |
| 9547380 | Connor M, Christie MJ: Modulation of Ca2+ channel currents of acutely dissociated rat periaqueductal grey neurons. J Physiol. 1998 May 15;509 ( Pt 1):47-58. Nociceptin (EC50, 5 nM) and baclofen (EC50, 0.8 microM) inhibited IBa in all PAG neurons, while the opioid agonist enkephalin (met-enkephalin; 300 nM-10 microM) inhibited IBa in 40 % of neurons. |
82(1,1,1,2) | Details |
| 9463438 | Adams DJ, Trequattrini C: Opioid receptor-mediated inhibition of omega-conotoxin GVIA-sensitive calcium channel currents in rat intracardiac neurons. J Neurophysiol. 1998 Feb;79(2):753-62. Half-maximal inhibition of Ba2+ current (IBa) amplitude was obtained with 270 nM Met-enkephalin or Leu-enkephalin. |
39(0,1,2,4) | Details |
| 15571668 | Ohta T, Kai T, Ito S: Evidence for paracrine modulation of voltage-dependent channels by amperometric analysis in cultured porcine chromaffin cells. Brain Res. 2004 Dec 31;1030(2):183-92. Application of (NA), ATP, -enkephalin (ENK) or protons decreased IBa. |
6(0,0,1,1) | Details |
| 10398877 | Morikawa H, Mima H, Uga H, Shoda T, Fukuda K: Opioid potentiation of N-type Ca2+ channel currents via pertussis-toxin-sensitive G proteins in NG108-15 cells. Pflugers Arch. 1999 Aug;438(3):423-6. In order to address this issue, we analyzed the effects of [d-Ala2, d-Leu5]-enkephalin (DADLE) on whole-cell Ba2+ currents (IBa) through voltage-gated Ca2+ channels in NG108-15 neuroblastoma x glioma hybrid cells. |
6(0,0,1,1) | Details |