| Name | integrin alpha M |
|---|---|
| Synonyms | CD11B; CD11b; CD11b antigen; CR 3 alpha chain; CR3A; Cell surface glycoprotein MAC 1 alpha subunit; ITGAM; Integrin alpha M beta 2… |
| Name | IBA |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17823975 | Ji KA, Yang MS, Jeong HK, Min KJ, Kang SH, Jou I, Joe EH: Resident microglia die and infiltrated neutrophils and monocytes become major inflammatory cells in lipopolysaccharide-injected brain. Glia. 2007 Nov 15;55(15):1577-88. To understand contribution of microglia and blood inflammatory cells to brain inflammation, the behavior of microglia, neutrophils, and monocytes was investigated in LPS (lipopolysaccharide)-injected substantia nigra pars compacta, cortex, and hippocampus of normal and/or leukopenic rats using specific markers of neutrophils (myeloperoxidase, MPO), and microglia and monocytes (ionized binding adaptor molecule-1, Iba-1), as well as a general marker for these inflammatory cells (CD11b). |
5(0,0,0,5) | Details |
| 17600341 | Xu H, Chen M, Mayer EJ, Forrester JV, Dick AD: Turnover of resident retinal microglia in the normal adult mouse. Glia. 2007 Aug 15;55(11):1189-98. Few (6.15 +/- 2.02 cells/retina) BrdU (+) cells were detected and of these some coexpressed CD11b (1.67 +/- 0.62 cells/retina) or F4/80 (0.57 +/- 0.30 cells/retina). |
1(0,0,0,1) | Details |
| 20002517 | Pifarre P, Prado J, Giralt M, Molinero A, Hidalgo J, Garcia A: Cyclic GMP phosphodiesterase inhibition alters the glial inflammatory response, reduces oxidative stress and cell death and increases angiogenesis following focal brain injury. J Neurochem. 2010 Feb;112(3):807-17. Epub 2009 Nov 30. In contrast, zaprinast decreased the number of round/ameboid lectin-positive cells and the expression of the activated microglia/macrophage markers Iba-1 and CD11b indicating decreased recruitment and activation of these cells. |
1(0,0,0,1) | Details |
| 12944523 | Babcock AA, Kuziel WA, Rivest S, Owens T: Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. J Neurosci. 2003 Aug 27;23(21):7922-30. A population of Mac1/CD11b+ CD45high macrophages (distinct from CD45low microglia) was specifically detected within the lesion-reactive hippocampus by 12 hr after injury. |
1(0,0,0,1) | Details |
| 17110040 | Moss A, Beggs S, Vega-Avelaira D, Costigan M, Hathway GJ, Salter MW, Fitzgerald M: Spinal microglia and neuropathic pain in young rats. Pain. 2007 Apr;128(3):215-24. Epub 2006 Nov 15. This was confirmed by qPCR analysis of IBA-1 mRNA and mRNA of other microglial markers, integrin-alpha M, MHC-II DMalpha and MHC-II DMbeta. |
1(0,0,0,1) | Details |
| 19913017 | Louboutin JP, Reyes BA, Agrawal L, Van Bockstaele EJ, Strayer DS: HIV-1 gp120-induced neuroinflammation: relationship to neuron loss and protection by rSV40-delivered antioxidant enzymes. Exp Neurol. 2010 Jan;221(1):231-45. Epub 2009 Nov 11. CD11b-positive microglia were increased 1 day post-challenge; Iba-1- and ED1-positive cells peaked at 7 days and 14 days. |
1(0,0,0,1) | Details |
| 16647243 | Frank MG, Baratta MV, Sprunger DB, Watkins LR, Maier SF: Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses. Brain Behav Immun. 2007 Jan;21(1):47-59. Epub 2006 May 2. The effect of inescapable shock (IS) on glial activation (MHC II, CD11b, Iba-1, and GFAP) and regulatory markers (CD200) in vivo, and microglia pro-inflammatory responses (interleukin-1beta; IL-1beta) to lipopolysaccharide (LPS) ex vivo, were assessed in rat hippocampus. |
1(0,0,0,1) | Details |