| Name | phosphodiesterase |
|---|---|
| Synonyms | CAMP specific phosphodiesterase variant PDE4A 10; CAMP specific phosphodiesterase variant TM3; CAMP specific phosphodiesterase; Cyclic AMP phosphodiesterase PDE4A11; Cyclic AMP specific phosphodiesterase HSPDE4A10; DPDE 2; DPDE2; PDE 4… |
| Name | IBA |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20002517 | Pifarre P, Prado J, Giralt M, Molinero A, Hidalgo J, Garcia A: Cyclic GMP phosphodiesterase inhibition alters the glial inflammatory response, reduces oxidative stress and cell death and increases angiogenesis following focal brain injury. J Neurochem. 2010 Feb;112(3):807-17. Epub 2009 Nov 30. |
3(0,0,0,3) | Details |
| 17047525 | Iba T, Kidokoro A, Fukunaga M, Takuhiro K, Ouchi M, Ito Y: Comparison of the protective effects of type III phosphodiesterase (PDE3) inhibitor (cilostazol) and on intestinal microcirculation after ischemia reperfusion injury in mice. Shock. 2006 Nov;26(5):522-6. |
1(0,0,0,1) | Details |
| 1326680 | Iba T, Mills I, Sumpio BE: Intracellular cyclic AMP levels in endothelial cells subjected to cyclic strain in vitro. J Surg Res. 1992 Jun;52(6):625-30. One hour prior to experimentation 5 mM IBMX, a phosphodiesterase inhibitor, was added. |
1(0,0,0,1) | Details |
| 17676428 | Takagi S, Hayakawa N, Kimoto H, Kato H, Araki T: Damage to oligodendrocytes in the striatum after MPTP neurotoxicity in mice. J Neural Transm. 2007;114(12):1553-7. Epub 2007 Aug 6. On the other hand, the levels of CNPase (2', 3'-cyclic nucleotide 3'-phosphodiesterase) protein were decreased significantly in the striatum 3 and 7 days after MPTP treatment. |
1(0,0,0,1) | Details |
| 9789110 | Sunagawa M, Yokoshiki H, Seki T, Sperelakis N: Intracellular application of calmidazolium increases Ca2+ current through activation of protein kinase A in cultured vascular smooth muscle cells. J Vasc Res. 1998 Sep-Oct;35(5):303-9. Since CMZ is a strong inhibitor of Ca2+/CaM-dependent phosphodiesterase (type I PDE), we studied the effect of 8-methoxymethyl-3-isobutyl-1-methylxanthine (MIBMX), another specific inhibitor of the PDE. The peak IBa (Ca2+ channel using 5 mM Ba2+ as charge carrier) was evoked every 15 s by a test potential to +10 mV from a holding potential of -60 mV. |
1(0,0,0,1) | Details |
| 19472050 | Kimoto H, Eto R, Abe M, Kato H, Araki T: Alterations of glial cells in the mouse hippocampus during postnatal development. Cell Mol Neurobiol. 2009 Dec;29(8):1181-9. Epub . Neuronal nuclei (NeuN), Glial fibrillary acidic protein (GFAP), 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase), and ionized binding adaptor molecule 1 (Iba 1) immunoreactivity were measured in 1-, 2-, 4-, and 8-week-old mice. |
1(0,0,0,1) | Details |
| 1328605 | Iguchi M, Nakajima T, Hisada T, Sugimoto T, Kurachi Y: On the mechanism of papaverine inhibition of the voltage-dependent Ca++ current in isolated smooth muscle cells from the guinea pig trachea. J Pharmacol Exp Ther. 1992 Oct;263(1):194-200. Papaverine (1-100 microM) inhibited the Ba++ inward current (IBa) through the voltage-dependent L-type Ca++ channel in a concentration-dependent fashion. |
0(0,0,0,0) | Details |