Protein Information

Name PPARbeta
Synonyms FAAR; NR1C2; NUC 1; NUC1; NUCI; NUCII; Nuclear hormone receptor 1; PPAR beta…

Compound Information

Name IBA
CAS

Reference List

PubMed Abstract RScore(About this table)
10585473 Basu-Modak S, Braissant O, Escher P, Desvergne B, Honegger P, Wahli W: Peroxisome proliferator-activated receptor beta regulates acyl-CoA synthetase 2 in reaggregated rat brain cell cultures. J Biol Chem. 1999 Dec 10;274(50):35881-8.


The biological roles of PPARalpha and PPARgamma are relatively well understood, but little is known about the function of PPARbeta.
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11971202 Wahli W: Peroxisome proliferator-activated receptors (PPARs): from metabolic control to epidermal wound healing. Swiss Med Wkly. 2002 Feb 23;132(7-8):83-91.


Three isotypes called PPARalpha, PPARbeta/delta and PPARgamma have been identified in lower vertebrates and mammals.
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19726504 Mizutani T, Ishizaka A, Tomizawa M, Okazaki T, Yamamichi N, Kawana-Tachikawa A, Iwamoto A, Iba H: Loss of the Brm-type SWI/SNF chromatin remodeling complex is a strong barrier to the Tat-independent transcriptional elongation of human immunodeficiency virus type 1 transcripts. J Virol. 2009 Nov;83(22):11569-80. Epub 2009 Sep 2.


Also, nuc-1 is remodeled by exogenous Brm in some integrants.
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9699859 Desvergne B, IJpenberg A, Devchand PR, Wahli W: The peroxisome proliferator-activated receptors at the cross-road of diet and hormonal signalling. J Steroid Biochem Mol Biol. 1998 Apr;65(1-6):65-74.


The function of the ubiquitously expressed isotype, PPAR beta, remains to be determined.
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