Protein Information

Name kappa opioid receptors
Synonyms Kappa opioid receptor; KOR 1; KOR1; Kappa type opioid receptor; OPRK; OPRK 1; OPRK1; Opioid receptor kappa 1…

Compound Information

Name IBA
CAS

Reference List

PubMed Abstract RScore(About this table)
9824718 Soldo BL, Moises HC: mu-opioid receptor activation inhibits N- and P-type Ca2+ channel currents in magnocellular neurones of the rat supraoptic nucleus. J Physiol. 1998 Dec 15;513 ( Pt 3):787-804.

The effects of local application of mu-, delta- or kappa-opioid receptor selective agonists were examined on specific components of high voltage-activated (HVA) IBa, pharmacologically isolated by use of Ca2+ channel-subtype selective antagonists. 2.
81(1,1,1,1) Details
7535119 Kaneko S, Fukuda K, Yada N, Akaike A, Mori Y, Satoh M: Ca2+ channel inhibition by kappa opioid receptors expressed in Xenopus oocytes. Neuroreport. 1994 Dec 20;5(18):2506-8.

Perfusion of the oocytes with U50488H inhibited depolarization-evoked Ba2+ current (IBa) in a reversible manner, showing maximal inhibition of 25% at 1 microM (IC50 = 31 nM).
3(0,0,0,3) Details
10323586 Connor M, Schuller A, Pintar JE, Christie MJ: Mu-opioid receptor modulation of calcium channel current in periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR-1. Br J Pharmacol. 1999 Apr;126(7):1553-8.


The actions of opioid receptor agonists on the calcium channel currents (IBa) of acutely dissociated periaqueductal grey (PAG) neurons from C57B16/J mice and mutant mice lacking the first exon of the mu-opioid receptor (MOR-1) were examined using whole cell patch clamp techniques.
0(0,0,0,0) Details
9463438 Adams DJ, Trequattrini C: Opioid receptor-mediated inhibition of omega-conotoxin GVIA-sensitive calcium channel currents in rat intracardiac neurons. J Neurophysiol. 1998 Feb;79(2):753-62.


Half-maximal inhibition of Ba2+ current (IBa) amplitude was obtained with 270 nM Met-enkephalin or Leu-enkephalin.
0(0,0,0,0) Details