Protein Information

Name synaptophysin
Synonyms Major synaptic vesicle protein p38; p38; Syp; Major syp38naptic vesicle protein; Synaptophysin; Major syp38naptic vesicle proteins; Synaptophysins

Compound Information

Name IBA
CAS

Reference List

PubMed Abstract RScore(About this table)
19486898 Jung SH, Lee ST, Chu K, Park JE, Lee SU, Han TR, Kim M: Cell proliferation and synaptogenesis in the cerebellum after focal cerebral ischemia. Brain Res. 2009 Aug 11;1284:180-90. Epub 2009 May 30.


BrdU+ cells and Iba-1+ cells were counted, and cerebellar synaptophysin immunoreactivity was quantitatively analyzed.
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19103252 Scorisa JM, Zanon RG, Freria CM, de Oliveira AL: Glatiramer acetate positively influences spinal motoneuron survival and synaptic plasticity after ventral root avulsion. Neurosci Lett. 2009 Feb 13;451(1):34-9. Epub 2008 Dec 16.


A correlation between the synaptic changes and glial activation was obtained by performing immunolabeling against synaptophysin, GFAP and Iba-1.
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18775685 Payes AC, Zanon RG, Pierucci A, Oliveira AL: MHC class I upregulation is not sufficient to rescue neonatal alpha motoneurons after peripheral axotomy. Brain Res. 2008 Oct 31;1238:23-30. Epub 2008 Aug 23.


The results were analyzed by counting Nissl stained motoneurons, immunohistochemistry (anti-synaptophysin, MHC class I, GFAP and Iba-1) and transmission electron microscopy.
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16247481 Watanabe H, Mizutani T, Haraguchi T, Yamamichi N, Minoguchi S, Yamamichi-Nishina M, Mori N, Kameda T, Sugiyama T, Iba H: SWI/SNF complex is essential for NRSF-mediated suppression of neuronal genes in human nonsmall cell lung carcinoma cell lines. Oncogene. 2006 Jan 19;25(3):470-9.


We also demonstrate that the strong transcriptional suppression of such neuron-specific genes as synaptophysin and SCG10 by NRSF in these non-neural cells requires the functional SWI/SNF complex; these neuronal genes were elevated in cell lines deficient in both Brm and BRG1, whereas retrovirus vectors expressing siRNAs targeting integral components of SWI/SNF complex (Brm/BRG1 or Ini1) induced expression of these neuronal genes in SWI/SNF-competent cell lines.
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19555463 Simoes GF, Oliveira AL: Alpha motoneurone input changes in dystrophic MDX mice after sciatic nerve transection. Neuropathol Appl Neurobiol. 2010 Feb;36(1):55-70. Epub 2009 Jun 25.


Seven days after surgery, the animals were sacrificed and the lumbar spinal cords processed for immunohistochemistry using antibodies to the major histocompatibility complex of class I (MHC I), synaptophysin, IBA-1 and glial fibrillary acidic protein (GFAP).
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