Protein Information

Name BRG1
Synonyms ATP dependent helicase SMARCA4; SNF2LB; SWI 2; SWI2; BAF190; SNF 2; SNF2; BRG 1…

Compound Information

Name IBA
CAS

Reference List

PubMed Abstract RScore(About this table)
12493776 Yamamichi-Nishina M, Ito T, Mizutani T, Yamamichi N, Watanabe H, Iba H: SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level. J Biol Chem. 2003 Feb 28;278(9):7422-30. Epub 2002 Dec 17.

6(0,0,0,6) Details
16247481 Watanabe H, Mizutani T, Haraguchi T, Yamamichi N, Minoguchi S, Yamamichi-Nishina M, Mori N, Kameda T, Sugiyama T, Iba H: SWI/SNF complex is essential for NRSF-mediated suppression of neuronal genes in human nonsmall cell lung carcinoma cell lines. Oncogene. 2006 Jan 19;25(3):470-9.


Mammalian chromatin remodeling factor, SWI/SNF complex contains a single molecule of either Brm or BRG1 as the ATPase catalytic subunit.
4(0,0,0,4) Details
18006815 Yamamichi N, Inada K, Ichinose M, Yamamichi-Nishina M, Mizutani T, Watanabe H, Shiogama K, Fujishiro M, Okazaki T, Yahagi N, Haraguchi T, Fujita S, Tsutsumi Y, Omata M, Iba H: Frequent loss of Brm expression in gastric cancer correlates with histologic features and differentiation state. Cancer Res. 2007 Nov 15;67(22):10727-35.


The mammalian SWI/SNF chromatin remodeling complex, an essential epigenetic regulator, contains either a single Brm or BRG1 molecule as its catalytic subunit.
2(0,0,0,2) Details
18042045 Ito T, Watanabe H, Yamamichi N, Kondo S, Tando T, Haraguchi T, Mizutani T, Sakurai K, Fujita S, Izumi T, Isobe T, Iba H: Brm transactivates the telomerase reverse transcriptase (TERT) gene and modulates the splicing patterns of its transcripts in concert with p54 (nrb). Biochem J. 2008 Apr 1;411(1):201-9.


We report that a DBHS (Drosophila behaviour, human splicing) family protein, p54 (nrb), binds both BRG1 (Brahma-related gene 1) and Brm (Brahma), catalytic subunits of the SWI/SNF (switch/sucrose non-fermentable) chromatin remodelling complex, and also another core subunit of this complex, BAF60a.
2(0,0,0,2) Details
16007216 Yamamichi N, Yamamichi-Nishina M, Mizutani T, Watanabe H, Minoguchi S, Kobayashi N, Kimura S, Ito T, Yahagi N, Ichinose M, Omata M, Iba H: The Brm gene suppressed at the post-transcriptional level in various human cell lines is inducible by transient HDAC inhibitor treatment, which exhibits antioncogenic potential. Oncogene. 2005 Aug 18;24(35):5471-81.


Each complex includes a single BRG1 or Brm molecule as the catalytic subunit.
2(0,0,0,2) Details