| Name | Nerve growth factor |
|---|---|
| Synonyms | Beta NGF; Beta nerve growth factor; Beta nerve growth factor precursor; HSAN 5; HSAN5; NGF; NGFB; Nerve growth factor… |
| Name | IBA |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7971149 | Bouron A, Reber BF: Differential modulation of pharmacologically distinct components of Ca2+ currents by protein kinase C activators and phosphatase inhibitors in nerve-growth-factor-differentiated rat pheochromocytoma (PC12) cells. Pflugers Arch. 1994 Jul;427(5-6):510-6. By using omega-conotoxin (CgTX) and isradipine, two specific Ca2+ channel blockers, we found three types of Ba2+ currents (IBa): (1) a omega-CgTX-sensitive IBa; (2) an isradipine-sensitive IBa; and (3) a omega-CgTX plus isradipine-resistant IBa. |
2(0,0,0,2) | Details |
| 9744944 | Lei S, Dryden WF, Smith PA: Involvement of Ras/MAP kinase in the regulation of Ca2+ channels in adult bullfrog sympathetic neurons by nerve growth factor. J Neurophysiol. 1998 Sep;80(3):1352-61. The increase in Ba2+ current (IBa) density induced by NGF was attenuated by the RNA synthesis inhibitor cordycepin (20 microM), by the DNA transcription inhibitor actinomycin D (0.01 microgram/ml), by inhibitors of Ras isoprenylation 0.1-1.0 mM or alpha-hydroxyfarnesylphosphonic acid 10-100 microM), by kinase inhibitors (20 microM) or lavendustin A (1 microM), and by PD98059 (10-100 microM), an inhibitor of mitogen-activated protein kinase kinase. |
2(0,0,0,2) | Details |
| 9195902 | Kobayashi M, Nagata S, Kita Y, Nakatsu N, Ihara S, Kaibuchi K, Kuroda S, Ui M, Iba H, Konishi H, Kikkawa U, Saitoh I, Fukui Y: Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. J Biol Chem. 1997 Jun 27;272(26):16089-92. It has been shown that inhibition of phosphatidylinositol (PI) 3-kinase blocks neurite outgrowth of PC12 cells stimulated with nerve growth factor. |
1(0,0,0,1) | Details |
| 1649292 | Shafer TJ, Atchison WD: Methylmercury blocks N- and L-type Ca++ channels in nerve growth factor-differentiated pheochromocytoma (PC12) cells. J Pharmacol Exp Ther. 1991 Jul 1;258(1):149-57. Based on biophysical characteristics and sensitivity to omega-conotoxin GVIA and dihydropyridine agonists and antagonists, voltage-activated Ba++ currents (IBa) in PC12 cells were mediated by N- and L-type Ca++ channels. |
1(0,0,0,1) | Details |
| 9405550 | Lei S, Dryden WF, Smith PA: Regulation of N- and L-type Ca2+ channels in adult frog sympathetic ganglion B cells by nerve growth factor in vitro and in vivo. J Neurophysiol. 1997 Dec;78(6):3359-70. To examine mechanisms responsible for the long-term regulation of Ca2+-channels in an adult neuron, changes in whole cell Ba2+ current (IBa) were examined in adult bullfrog sympathetic ganglion B cells in vitro. |
1(0,0,0,1) | Details |