Protein Information

Name fatty acid desaturase
Synonyms Acyl CoA desaturase; Acyl Coenzyme A desaturase; Delta(9) desaturase; Delta 9 desaturase; FADS 5; FADS5; Fatty acid desaturase; PRO0998…

Compound Information

Name IBA
CAS

Reference List

PubMed Abstract RScore(About this table)
8866893 Hamada T, Kodama H, Nishimura M, Iba K: Modification of fatty acid composition by over- and antisense-expression of a microsomal omega-3 fatty acid desaturase gene in transgenic tobacco. Transgenic Res. 1996 Mar;5(2):115-21.

3(0,0,0,3) Details
9049269 Kodama H, Akagi H, Kusumi K, Fujimura T, Iba K: Structure, chromosomal location and expression of a rice gene encoding the microsome omega-3 fatty acid desaturase. Plant Mol Biol. 1997 Feb;33(3):493-502.

3(0,0,0,3) Details
16786241 Hamada T, Iba K, Shimada T: Reduction of trienoic fatty acid content by expression of a double-stranded RNA of a plastid omega-3 fatty acid desaturase gene in transgenic tobacco. Biotechnol Lett. 2006 Jun;28(11):779-85. Epub 2006 May 23.

3(0,0,0,3) Details
8819308 Hamada T, Nishiuchi T, Kodama H, Nishimura M, Iba K: cDNA cloning of a wounding-inducible gene encoding a plastid omega-3 fatty acid desaturase from tobacco. Plant Cell Physiol. 1996 Jul;37(5):606-11.

2(0,0,0,2) Details
11135114 Horiguchi G, Fuse T, Kawakami N, Kodama H, Iba K: Temperature-dependent translational regulation of the ER omega-3 fatty acid desaturase gene in wheat root tips. Plant J. 2000 Dec;24(6):805-13.

2(0,0,0,2) Details
15545277 Matsuda O, Sakamoto H, Hashimoto T, Iba K: A temperature-sensitive mechanism that regulates post-translational stability of a plastidial omega-3 fatty acid desaturase (FAD8) in Arabidopsis leaf tissues. J Biol Chem. 2005 Feb 4;280(5):3597-604. Epub 2004 Nov 15.

2(0,0,0,2) Details
9765545 Hamada T, Kodama H, Takeshita K, Utsumi H, Iba K: Characterization of transgenic tobacco with an increased alpha-linolenic acid level . Plant Physiol. 1998 Oct;118(2):591-8.


Microsomal omega-3 fatty acid desaturase catalyzes the conversion of 18:2 (linoleic acid) to 18:3 (alpha-linolenic acid) in phospholipids, which are the main constituents of extrachloroplast membranes.
2(0,0,0,2) Details
12228424 Kodama H, Horiguchi G, Nishiuchi T, Nishimura M, Iba K: Fatty Acid Desaturation during Chilling Acclimation Is One of the Factors Involved in Conferring Low-Temperature Tolerance to Young Tobacco Leaves. Plant Physiol. 1995 Apr;107(4):1177-1185.


The FAD7 gene, a gene for a chloroplast [omega]-3 fatty acid desaturase, is responsible for the trienoic fatty acid (TA) formation in leaf tissues.
2(0,0,0,2) Details
8534855 Nishiuchi T, Nakamura T, Abe T, Kodama H, Nishimura M, Iba K: Tissue-specific and light-responsive regulation of the promoter region of the Arabidopsis thaliana chloroplast omega-3 fatty acid desaturase gene (FAD7). Plant Mol Biol. 1995 Nov;29(3):599-609.

2(0,0,0,2) Details
12232227 Kodama H, Hamada T, Horiguchi G, Nishimura M, Iba K: Genetic Enhancement of Cold Tolerance by Expression of a Gene for Chloroplast [omega]-3 Fatty Acid Desaturase in Transgenic Tobacco. Plant Physiol. 1994 Jun;105(2):601-605.

2(0,0,0,2) Details
10814818 Kodama H, Nishiuchi T, Seo S, Ohashi Y, Iba K: Possible involvement of protein phosphorylation in the wound-responsive expression of Arabidopsis plastid omega-3 fatty acid desaturase gene. Plant Sci. 2000 Jun 29;155(2):153-160.

2(0,0,0,2) Details
9368411 Nishiuchi T, Hamada T, Kodama H, Iba K: Wounding changes the spatial expression pattern of the arabidopsis plastid omega-3 fatty acid desaturase gene (FAD7) through different signal transduction pathways. Plant Cell. 1997 Oct;9(10):1701-12.

2(0,0,0,2) Details
9484441 Berberich T, Harada M, Sugawara K, Kodama H, Iba K, Kusano T: Two maize genes encoding omega-3 fatty acid desaturase and their differential expression to temperature. Plant Mol Biol. 1998 Jan;36(2):297-306.

2(0,0,0,2) Details
11722119 Matsuda O, Watanabe C, Iba K: Hormonal regulation of tissue-specific ectopic expression of an Arabidopsis endoplasmic reticulum-type omega-3 fatty acid desaturase (FAD3) gene. Planta. 2001 Oct;213(6):833-40.

2(0,0,0,2) Details
7926817 Hamada T, Kodama H, Nishimura M, Iba K: Cloning of a cDNA encoding tobacco omega-3 fatty acid desaturase. . Gene. 1994 Sep 30;147(2):293-4.

1(0,0,0,1) Details
15327985 Tomita R, Hamada T, Horiguchi G, Iba K, Kodama H: Transgene overexpression with cognate small interfering RNA in tobacco. FEBS Lett. 2004 Aug 27;573(1-3):117-20.


A tobacco endoplasmic reticulum omega-3 fatty acid desaturase (NtFAD3) catalyzes the formation of alpha-linolenate (18:3).
1(0,0,0,1) Details
8226956 Iba K, Gibson S, Nishiuchi T, Fuse T, Nishimura M, Arondel V, Hugly S, Somerville C: A gene encoding a chloroplast omega-3 fatty acid desaturase complements alterations in fatty acid desaturation and chloroplast copy number of the fad7 mutant of Arabidopsis thaliana. J Biol Chem. 1993 Nov 15;268(32):24099-105.

1(0,0,0,1) Details
7855303 Iba K, Kodama H: [Omega-3 fatty acid desaturase genes and genetically engineered enhancement of cold tolerance in higher plants] Tanpakushitsu Kakusan Koso. 1994 Dec;39(16):2803-13.

1(0,0,0,1) Details
10642547 Murakami Y, Tsuyama M, Kobayashi Y, Kodama H, Iba K: Trienoic fatty acids and plant tolerance of high temperature. Science. 2000 Jan 21;287(5452):476-9.


Transgenic tobacco plants in which the gene encoding chloroplast omega-3 fatty acid desaturase, which synthesizes trienoic fatty acids, was silenced contained a lower level of trienoic fatty acids than wild-type plants and were better able to acclimate to higher temperatures.
1(0,0,0,1) Details
8066143 Nishiuchi T, Nishimura M, Arondel V, Iba K: Genomic nucleotide sequence of a gene encoding a microsomal omega-3 fatty acid desaturase from Arabidopsis thaliana. Plant Physiol. 1994 Jun;105(2):767-8.

1(0,0,0,1) Details
9880919 Wakita Y, Otani M, Iba K, Shimada T: Co-integration, co-expression and co-segregation of an unlinked selectable marker gene and NtFAD3 gene in transgenic rice plants produced by particle bombardment. Genes Genet Syst. 1998 Aug;73(4):219-26.


Using the scutellar tissue of rice mature embryos as a target tissue, a selectable marker gene, bar, and an unselectable gene, fatty acid desaturase gene from tobacco (NtFAD3), on separate plasmids, were introduced by particle bombardment.
1(0,0,0,1) Details
16415067 Yaeno T, Saito B, Katsuki T, Iba K: Ozone-induced expression of the Arabidopsis FAD7 gene requires salicylic acid, but not NPR1 and SID2. Plant Cell Physiol. 2006 Mar;47(3):355-62. Epub 2006 Jan 13.


The Arabidopsis FAD7 gene encodes a plastid omega-3 fatty acid desaturase that catalyzes the desaturation of dienoic fatty acids to trienoic fatty acids in chloroplast membrane lipids.
1(0,0,0,1) Details
18764923 Matsuda O, Sakamoto H, Nakao Y, Oda K, Iba K: CTD phosphatases in the attenuation of wound-induced transcription of jasmonic acid biosynthetic genes in Arabidopsis. Plant J. 2009 Jan;57(1):96-108. Epub 2008 Aug 29.


Arabidopsis FAD7 encodes a plastidial omega-3 fatty acid desaturase, which catalyses the production of TAs.
1(0,0,0,1) Details