Protein Information

Name galanin
Synonyms GAL; GAL 1; GAL1; GALN; GLNN; GMAP; Galanin; Galanin message associated peptide…

Compound Information

Name IBA
CAS

Reference List

PubMed Abstract RScore(About this table)
7543943 Merriam LA, Parsons RL: Neuropeptide galanin inhibits omega-conotoxin GVIA-sensitive calcium channels in parasympathetic neurons. J Neurophysiol. 1995 Apr;73(4):1374-82.

Galanin produced a concentration-dependent inhibition of IBa.
202(2,3,4,7) Details
9928168 Parsons RL, Mulvaney JM, Merriam LA: Galanin activates an inwardly rectifying potassium conductance and inhibits a voltage-dependent calcium conductance in mudpuppy parasympathetic neurons. Ann N Y Acad Sci. 1998 Dec 21;863:156-69.

Galanin-induced activation of an inwardly rectifying membrane potassium (K+) current and inhibition of barium current (IBa) were studied using whole cell voltage clamp recording techniques in parasympathetic neurons dissociated from the mudpuppy cardiac ganglion.
167(2,2,2,7) Details
8666034 Mulvaney JM, Merriam LA, Parsons RL: Galantide distinguishes putative subtypes of galanin receptors in mudpuppy parasympathetic neurons. Eur J Pharmacol. 1995 Dec 4;287(1):97-100.

Galantide acted like galanin and inhibited the voltage-dependent Ba2+ current (IBa).
115(1,2,2,5) Details
18602374 Endoh T, Sato D, Wada Y, Shibukawa Y, Ishihara K, Hashimoto S, Yoshinari M, Matsuzaka K, Tazaki M, Inoue T: Galanin inhibits calcium channels via Galpha (i)-protein mediated by GalR1 in rat nucleus tractus solitarius. Brain Res. 2008 Sep 10;1229:37-46. Epub 2008 Jun 20.

The purpose of this study was to investigate the effects of GAL on VDCCs currents (ICa) carried by Ba2+ (IBa) in the NTS using patch-clamp recording methods.
2(0,0,0,2) Details
1326680 Iba T, Mills I, Sumpio BE: Intracellular cyclic AMP levels in endothelial cells subjected to cyclic strain in vitro. J Surg Res. 1992 Jun;52(6):625-30.


After 10-60 min of cyclic strain, or upon exposure of EC to 100 microM forskolin or 0.1 microM galanin, intracellular cyclic AMP (cAMP) was measured by radioimmunoassay.
2(0,0,0,2) Details