Name | CYP1A1 |
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Synonyms | AHH; AHRR; Arylhydrocarbon hydroxylase; CP11; CYP 1; CYP1; CYP1A1; CYPIA 1… |
Name | IBA |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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12147272 | Iba MM, Nguyen T, Fung J: CYP1A1 induction by and its metabolites in HepG2 cells. Arch Biochem Biophys. 2002 Aug 15;404(2):326-34. |
8(0,0,0,8) | Details |
11485833 | Wei C, Caccavale RJ, Kehoe JJ, Thomas PE, Iba MM: CYP1A2 is expressed along with CYP1A1 in the human lung. . Cancer Lett. 2001 Sep 28;171(1):113-20. |
6(0,0,0,6) | Details |
11166912 | Wei C, Cacavale RJ, Kehoe JJ, Thomas PE, Iba MM: CYP1A2 is expressed along with CYP1A1 in the human lung. . Cancer Lett. 2001 Mar 10;164(1):25-32. |
6(0,0,0,6) | Details |
10413312 | Iba MM, Alam J, Touchard C, Thomas PE, Ghosal A, Fung J: Coordinate up-regulation of CYP1A1 and heme oxygenase-1 (HO-1) expression and modulation of synthase and tryptophan pyrrolase activities in -treated rats. Biochem Pharmacol. 1999 Aug 15;58(4):723-34. |
5(0,0,0,5) | Details |
16678472 | Iba MM, Fung J, Chung L, Zhao J, Winnik B, Buckley BT, Chen LC, Zelikoff JT, Kou YR: Differential inducibility of rat pulmonary CYP1A1 by cigarette smoke and wood smoke. Mutat Res. 2006 Jul 14;606(1-2):1-11. Epub 2006 May 5. |
5(0,0,0,5) | Details |
9764926 | Iba MM, Scholl H, Fung J, Thomas PE, Alam J: Induction of pulmonary CYP1A1 by . Xenobiotica. 1998 Sep;28(9):827-43. |
5(0,0,0,5) | Details |
11849738 | Wei C, Caccavale RJ, Weyand EH, Chen S, Iba MM: Induction of CYP1A1 and CYP1A2 expressions by prototypic and atypical inducers in the human lung. Cancer Lett. 2002 Apr 8;178(1):25-36. |
4(0,0,0,4) | Details |
10460794 | Iba MM, Fung J, Pak YW, Thomas PE, Fisher H, Sekowski A, Halladay AK, Wagner GC: Dose-dependent up-regulation of rat pulmonary, renal, and hepatic cytochrome P-450 (CYP) 1A expression by feeding. Drug Metab Dispos. 1999 Sep;27(9):977-82. In the present study, we examined the dose-CYP1A1/2 induction response relationship and the tissue specificity of the induction by orally administered which lacks the toxicity of the parenterally administered drug. |
4(0,0,0,4) | Details |
9858665 | Fung J, Thomas PE, Iba MM: Cytochrome P450 1A1 in rat peripheral blood lymphocytes: inducibility in vivo and bioactivation of benzo [a] pyrene in the Salmonella typhimurium mutagenicity assay in vitro. Mutat Res. 1999 Jan 2;438(1):1-12. |
4(0,0,0,4) | Details |
14574441 | Iba MM, Storch A, Ghosal A, Bennett S, Reuhl KR, Lowndes HE: Constitutive and inducible levels of CYP1A1 and CYP1A2 in rat cerebral cortex and cerebellum. Arch Toxicol. 2003 Oct;77(10):547-54. Epub 2003 Jul 11. |
4(0,0,0,4) | Details |
11585058 | Iba MM, Fung J: Pulmonary Cyp1A1 and CYP1A2 levels and activities in adult male and female offspring of rats exposed during gestation and lactation to 2,3,7, 8-tetrachlorodibenzo-p-dioxin. Biochem Pharmacol. 2001 Sep 1;62(5):617-26. |
4(0,0,0,4) | Details |
10704945 | Iba MM, Fung J, Cooper KR, Thomas PE, Wagner GC, Park Y: Effect of gestational and lactational 2,3,7, 8-tetrachlorodibenzo-p-dioxin exposure on the level and catalytic activities of hepatic microsomal CYP1A in prepubertal and adult rats. Biochem Pharmacol. 2000 May 1;59(9):1147-54. We determined the inducibility, as well as the persistence of the induction, of hepatic microsomal CYP1A1 and CYP1A2 (by western blot analysis), and their catalytic activities (as measured by resorufin ether O-dealkylation) in prepubertal (25-day-old) and adult (120-day-old) offspring of timed-pregnant Sprague-Dawley rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). |
3(0,0,0,3) | Details |
10860547 | Iba MM, Fung J, Giannone JV, Okey AB: Comparative induction of CYP1A1 expression by and its metabolites. Arch Biochem Biophys. 2000 Jun 15;378(2):299-310. |
3(0,0,0,3) | Details |
10594335 | Iba MM, Fung J: Induction of pulmonary cytochrome P4501A1: interactive effects of mecamylamine. Eur J Pharmacol. 1999 Nov 3;383(3):399-403. The effect of the nicotinic receptor antagonist mecamylamine on -mediated convulsions and induction of pulmonary cytochrome P4501A1 (CYP1A1) was examined in the rat. |
and 3(0,0,0,3) | Details |
8287374 | Iba MM, Bennett S, Storch A, Ghosal A, Thomas PE: Synergistic induction of rat microsomal CYP1A1 and CYP1A2 by in combination with Cancer Lett. 1993 Oct 15;74(1-2):69-74. |
3(0,0,0,3) | Details |
6838636 | Iba MM, Sikka HC: Induction of hepatic microsomal cytochrome P-448-mediated oxidases by 3,3'-dichlorobenzidine in the rat. Biochem Pharmacol. 1983 Mar 1;32(5):901-9. Arylhydrocarbon hydroxylase activity was stimulated 5-fold by dichlorobenzidine pretreatment in comparison with a 12-fold stimulation following 3-methylcholanthrene pretreatment. |
1(0,0,0,1) | Details |
10463385 | Iba MM, Fung J, Thomas PE, Park Y: Constitutive and induced expression by Adult male and female Sprague-Dawley rats were compared in terms of the constitutive levels and inducibility of CYP1A1 and CYP1A2 (CYP1A) in lung, kidney, and liver. |
and beta-naphthoflavone of rat CYP1A is sexually dimorphic. Arch Toxicol. 1999 Jun-Jul;73(4-5):208-16.1(0,0,0,1) | Details |