Protein Information

Name calcineurin (protein family or complex)
Synonyms Calcineurin; Calcineurins; Protein phosphatase 2B

Compound Information

Name IBA
CAS

Reference List

PubMed Abstract RScore(About this table)
16928959 Deng L, Sugiura R, Takeuchi M, Suzuki M, Ebina H, Takami T, Koike A, Iba S, Kuno T: Real-time monitoring of calcineurin activity in living cells: evidence for two distinct Ca2+-dependent pathways in fission yeast. Mol Biol Cell. 2006 Nov;17(11):4790-800. Epub 2006 Aug 23.

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11448755 Cousson A: Pharmacological evidence for the implication of both cyclic GMP-dependent and -independent transduction pathways within auxin-induced stomatal opening in Commelina communis (L.). Plant Sci. 2001 Jul;161(2):249-258.


The CaM antagonists W-7 (in the 10-20 &mgr;M range) and N-(aminohexyl)-1-naphthalenesulphonamide (40 &mgr;M), the potential inhibitors of plant protein kinases 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (20 and 200 &mgr;M) and K-252a (0.6 &mgr;M), and cyclosporine A and FK506, potential inhibitors of plant homologs of Ca (2+)-CaM complex (Ca (2+)/CaM)-dependent protein phosphatase 2B, prevented the IBA and 8-Br-cGMP responses by about 70% and 100%, respectively.
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