| Name | CYP1A2 |
|---|---|
| Synonyms | CP12; CYP1A2; CYPIA 2; CYPIA2; Cytochrome P450 1A2; Dioxin inducible P3 450; P(3)450; P3 450… |
| Name | IBA |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 14574441 | Iba MM, Storch A, Ghosal A, Bennett S, Reuhl KR, Lowndes HE: Constitutive and inducible levels of CYP1A1 and CYP1A2 in rat cerebral cortex and cerebellum. Arch Toxicol. 2003 Oct;77(10):547-54. Epub 2003 Jul 11. |
5(0,0,0,5) | Details |
| 11585058 | Iba MM, Fung J: Pulmonary Cyp1A1 and CYP1A2 levels and activities in adult male and female offspring of rats exposed during gestation and lactation to 2,3,7, 8-tetrachlorodibenzo-p-dioxin. Biochem Pharmacol. 2001 Sep 1;62(5):617-26. |
5(0,0,0,5) | Details |
| 11166912 | Wei C, Cacavale RJ, Kehoe JJ, Thomas PE, Iba MM: CYP1A2 is expressed along with CYP1A1 in the human lung. . Cancer Lett. 2001 Mar 10;164(1):25-32. |
4(0,0,0,4) | Details |
| 11485833 | Wei C, Caccavale RJ, Kehoe JJ, Thomas PE, Iba MM: CYP1A2 is expressed along with CYP1A1 in the human lung. . Cancer Lett. 2001 Sep 28;171(1):113-20. |
4(0,0,0,4) | Details |
| 11849738 | Wei C, Caccavale RJ, Weyand EH, Chen S, Iba MM: Induction of CYP1A1 and CYP1A2 expressions by prototypic and atypical inducers in the human lung. Cancer Lett. 2002 Apr 8;178(1):25-36. |
3(0,0,0,3) | Details |
| 8287374 | Iba MM, Bennett S, Storch A, Ghosal A, Thomas PE: Synergistic induction of rat microsomal CYP1A1 and CYP1A2 by in combination with Cancer Lett. 1993 Oct 15;74(1-2):69-74. |
3(0,0,0,3) | Details |
| 10704945 | Iba MM, Fung J, Cooper KR, Thomas PE, Wagner GC, Park Y: Effect of gestational and lactational 2,3,7, 8-tetrachlorodibenzo-p-dioxin exposure on the level and catalytic activities of hepatic microsomal CYP1A in prepubertal and adult rats. Biochem Pharmacol. 2000 May 1;59(9):1147-54. We determined the inducibility, as well as the persistence of the induction, of hepatic microsomal CYP1A1 and CYP1A2 (by western blot analysis), and their catalytic activities (as measured by resorufin ether O-dealkylation) in prepubertal (25-day-old) and adult (120-day-old) offspring of timed-pregnant Sprague-Dawley rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). |
2(0,0,0,2) | Details |
| 10460794 | Iba MM, Fung J, Pak YW, Thomas PE, Fisher H, Sekowski A, Halladay AK, Wagner GC: Dose-dependent up-regulation of rat pulmonary, renal, and hepatic cytochrome P-450 (CYP) 1A expression by feeding. Drug Metab Dispos. 1999 Sep;27(9):977-82. administered in a nutritionally balanced liquid diet, at a level of 20 (low), 60 (medium), or 200 (high) mg/kg of diet, induced CYP1A1 in the lung and kidney in a dose-dependent manner and in the liver at the high dose only, whereas CYP1A2 was induced in the liver dose-dependently and in the kidney at the high dose only. |
2(0,0,0,2) | Details |
| 10413312 | Iba MM, Alam J, Touchard C, Thomas PE, Ghosal A, Fung J: Coordinate up-regulation of CYP1A1 and heme oxygenase-1 (HO-1) expression and modulation of synthase and tryptophan pyrrolase activities in -treated rats. Biochem Pharmacol. 1999 Aug 15;58(4):723-34. Increased hepatic CYP1A1 or CYP1A2 activity was preceded by increased activities of HO-1 and ALAS. |
1(0,0,0,1) | Details |
| 9764926 | Iba MM, Scholl H, Fung J, Thomas PE, Alam J: Induction of pulmonary CYP1A1 by . Xenobiotica. 1998 Sep;28(9):827-43. We have examined the catalytic activities (7-ethoxyresorufin O-deethylase [EROD] and 7-methoxyresorufin O-demethylase [MROD]), protein levels (Western blot analysis) and mRNA levels (Northern blot analysis) of cytochrome P4501A (CYP1A1 and CYP1A2) in the lung, liver and kidney following a single 2.5 mg/kg (15.4 micromol/kg) subcutaneous dose of to the female Sprague-Dawley rat. 2. |
1(0,0,0,1) | Details |
| 10463385 | Iba MM, Fung J, Thomas PE, Park Y: Constitutive and induced expression by and beta-naphthoflavone of rat CYP1A is sexually dimorphic. Arch Toxicol. 1999 Jun-Jul;73(4-5):208-16. Adult male and female Sprague-Dawley rats were compared in terms of the constitutive levels and inducibility of CYP1A1 and CYP1A2 (CYP1A) in lung, kidney, and liver. |
1(0,0,0,1) | Details |