| Name | c Src |
|---|---|
| Synonyms | ASV; SRC1; Avian sarcoma virus protein; Proto oncogene tyrosine protein kinase SRC; SRC; Tyrosine kinase pp60c src; Tyrosine protein kinase SRC 1; c SRC… |
| Name | IBA |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2426577 | Iba H, Jove R, Hanafusa H: Lack of induction of neuroretinal cell proliferation by Rous sarcoma virus variants that carry the c-src gene. Mol Cell Biol. 1985 Oct;5(10):2856-9. |
1(0,0,0,1) | Details |
| 2582237 | Johnson PJ, Coussens PM, Danko AV, Shalloway D: Overexpressed pp60c-src can induce focus formation without complete transformation of NIH 3T3 cells. Mol Cell Biol. 1985 May;5(5):1073-83. Iba, T. |
5(0,0,0,5) | Details |
| 6087323 | Iba H, Takeya T, Cross FR, Hanafusa T, Hanafusa H: Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblasts. Proc Natl Acad Sci U S A. 1984 Jul;81(14):4424-8. The transforming activity of the cellular src (c-src) gene as well as of hybrid genes between viral and cellular src was tested by constructing derivatives of Rous sarcoma virus DNA in which all or part of the viral src gene (v-src) was replaced by the corresponding portion of the c-src gene. |
4(0,0,0,4) | Details |
| 2424022 | Levy JB, Iba H, Hanafusa H: Activation of the transforming potential of p60c-src by a single amino acid change. Proc Natl Acad Sci U S A. 1986 Jun;83(12):4228-32. However, viral stocks isolated from cells transfected with Rous sarcoma virus DNA containing the c-src gene in place of the viral src gene did occasionally produce foci. |
3(0,0,0,3) | Details |
| 2432397 | Kato JY, Takeya T, Grandori C, Iba H, Levy JB, Hanafusa H: Amino acid substitutions sufficient to convert the nontransforming p60c-src protein to a transforming protein. Mol Cell Biol. 1986 Dec;6(12):4155-60. Since there are only six amino acid changes between p60c-src and p60v-src within the sequences upstream from BglI, we constructed chimeric molecules involving v-src and c-src to determine the effect of each amino acid substitution on the biological activities of the gene product. |
2(0,0,0,2) | Details |
| 2582236 | Iba H, Cross FR, Garber EA, Hanafusa H: Low level of cellular protein phosphorylation by nontransforming overproduced p60c-src. Mol Cell Biol. 1985 May;5(5):1058-66. We found that these phosphorylations were only slightly increased in the c-src-containing virus-infected cells, whereas both levels were significantly increased by infection with wild-type Rous sarcoma virus, or transforming mutant viruses which are derived from c-src-containing viruses by spontaneous mutation. |
1(0,0,0,1) | Details |
| 3023673 | Jove R, Mayer BJ, Iba H, Laugier D, Poirier F, Calothy G, Hanafusa T, Hanafusa H: Genetic analysis of p60v-src domains involved in the induction of different cell transformation parameters. J Virol. 1986 Dec;60(3):840-8. Amino- and carboxy-terminal coding regions of the cloned mutant genes were exchanged with the corresponding regions of cloned wild-type v-src and chicken c-src genes, reconstructed into viral DNA, and expressed in infected cells maintained at various temperatures. |
1(0,0,0,1) | Details |
| 2463379 | Sato M, Kato J, Takeya T: Characterization of partially activated p60c-src in chicken embryo fibroblasts. J Virol. 1989 Feb;63(2):683-8. We show here that p60c-src that had been converted to transforming protein by amino acid substitution of the c-src gene either at position 63, 95 and 96, or 338 (J. Iba, J. |
1(0,0,0,1) | Details |
| 9914387 | Seki T, Yokoshiki H, Sunagawa M, Nakamura M, Sperelakis N: Angiotensin II stimulation of Ca2+-channel current in vascular smooth muscle cells is inhibited by lavendustin-A and LY-294002. Pflugers Arch. 1999 Feb;437(3):317-23. A non-receptor Tyr-PK, pp60 (c-src), and PKC have been reported to stimulate the Ca2+ channels in VSM cells. Application of 50 nM AngII significantly increased the amplitude of Ba2+ currents through the voltage-gated Ca2+ channels (IBa) by 34. 5+/-9.1% (n=10) within 1 min. |
1(0,0,0,1) | Details |