| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | IBA |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 3429766 | Iba MM: Inhibition of hepatic microsomal lipid peroxidation by endogenous in the rat. J Appl Toxicol. 1987 Dec;7(6):397-401. The indices of lipid peroxidation examined included the rate of -dependent formation of malondialdehyde (MDA) and the concomitant destruction of cytochrome P-450 and decline in the linearity of benzphetamine N-demethylase activity in microsomes. |
4(0,0,0,4) | Details |
| 3309638 | Iba MM: Comparative activation of 3,3'-dichlorobenzidine and related benzidines to mutagens in the Salmonella typhimurium assay by hepatic S9 and microsomes from rats pretreated with different inducers of cytochrome P-450. Mutat Res. 1987 Oct;182(5):231-41. |
4(0,0,0,4) | Details |
| 3579983 | Iba MM, Mannering GJ: - and hydroperoxide-induced lipid peroxidation and destruction of cytochrome P-450 in hepatic microsomes. Biochem Pharmacol. 1987 May 1;36(9):1447-55. |
3(0,0,0,3) | Details |
| 10460794 | Iba MM, Fung J, Pak YW, Thomas PE, Fisher H, Sekowski A, Halladay AK, Wagner GC: Dose-dependent up-regulation of rat pulmonary, renal, and hepatic cytochrome P-450 (CYP) 1A expression by feeding. Drug Metab Dispos. 1999 Sep;27(9):977-82. |
2(0,0,0,2) | Details |
| 3345196 | Iba MM, Lang B: Stimulation of the conjugation of lipid dienes in hepatic microsomes by 3,3'-dichlorobenzidine. Biochem Pharmacol. 1988 Mar 1;37(5):781-91. It is postulated that a metabolite of DCB generated by cytochrome P-450 reacts with membrane lipids both in vivo and in vitro in a manner analogous to the initiation of lipid peroxidation but at the same time prevents the autocatalytic decomposition of the lipids. |
1(0,0,0,1) | Details |
| 10413312 | Iba MM, Alam J, Touchard C, Thomas PE, Ghosal A, Fung J: Coordinate up-regulation of CYP1A1 and heme oxygenase-1 (HO-1) expression and modulation of synthase and tryptophan pyrrolase activities in -treated rats. Biochem Pharmacol. 1999 Aug 15;58(4):723-34. To determine the changes in heme metabolism associated with induction of cytochrome P450 expression by we compared the time course of CYP1A expression with the time course of (i) expression of heme oxygenase-1 (HO-1) (EC 1.14.99.3), (ii) activity of synthetase (ALAS) (EC 2.3.1.37), and (iii) heme saturation of tryptophan pyrrolase (TPO) (EC 1.13.11.11) in tissues of rats administered a single 100 or 150 mg/kg i.p. dose of |
1(0,0,0,1) | Details |
| 8498086 | Iba MM, Gander JE, Mannering GJ: Lipid peroxidation-cytochrome P450 interactions. Xenobiotica. 1993 Mar;23(3):227-39. |
1(0,0,0,1) | Details |
| 3130202 | Iba MM, Thomas PE: Activation of 3,3'-dichlorobenzidine in rat liver microsomes to mutagens: involvement of cytochrome P-450d. Carcinogenesis. 1988 May;9(5):717-23. Studies were carried out, using antibodies to specific cytochrome P-450 isozymes, to identify the isozymes involved in the -dependent activation of 3,3'-dichlorobenzidine (DCB) by rat hepatic microsomes to mutagens in the Ames test. |
1(0,0,0,1) | Details |
| 7207459 | Nerland DE, Iba MM, Mannering GJ: Use of hydroperoxide in the determination of absolute spectra of membrane-bound cytochrome P-450. Mol Pharmacol. 1981 Jan;19(1):162-7. |
1(0,0,0,1) | Details |