| Name | thymidylate synthase |
|---|---|
| Synonyms | HsT422; TS; TMS; TSase; TYMS; Thymidylate synthase; Thymidylate synthetase; Thymidylate synthetase variant… |
| Name | IBA |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7979418 | Iba T, Yagi Y, Kidokoro A, Fukunaga M, Uchida J: [The mechanism of biochemical modulation in methotrexate/5-fluorouracil sequential chemotherapy]. Gan To Kagaku Ryoho. 1994 Nov;21(15):2591-4. In this study, we investigated the relationship between antitumor activity and the inhibition of thymidylate synthase and between antitumor activity and incorporation of 5-FU into RNA (F-RNA) in mice bearing Sarcoma-180 treated by tegafur alone (100 mg/kg) or by the combination of MTX (42 mg/kg) and tegafur (100 mg/kg). |
2(0,0,0,2) | Details |
| 9679579 | Iba T, Yagi Y, Kidokoro A, Ishi K, Koyatsu J: [The intratumoral levels of thymidylate synthetase and in gastric and colon cancer]. Gan To Kagaku Ryoho. 1998 Jul;25(8):1165-71. |
2(0,0,0,2) | Details |
| 8678515 | Iba T, Yagi Y, Kidokoro A, Ishi K, Koyatsu J: [Changes in levels after cisplatin treatment of gastric cancer] . Gan To Kagaku Ryoho. 1996 Apr;23(5):573-7. Four hrs later, the stomach was resected and levels were measured in the tumor and normal mucosa by thymidylate synthase binding assay. |
1(0,0,0,1) | Details |
| 14712768 | Iba T, Kidokoro A, Fukunaga M, Sugiyama K, Fukunaga T, Aihara N: [Effect and mechanism of orally administered /5-fluorouracil on colon cancer]. Gan To Kagaku Ryoho. 2003 Dec;30(13):2077-81. Tumor volume, thymidylate synthase inhibition rate (TSIR), incorporation of 5-FU into RNA (F-RNA) and body weight were measured at the end of the treatment. |
1(0,0,0,1) | Details |
| 8452385 | Iba T, Yagi Y, Kidokoro A, Fukunaga T: [Comparison between and cisplatin as a modulator of 5-fluorouracil]. Gan To Kagaku Ryoho. 1993 Mar;20(4):479-83. Two hrs. later, CH2-FH4 levels were measured in tumor, muscle and intestine by thymidylate synthase (TS) binding assay. |
1(0,0,0,1) | Details |
| 10234293 | Iba T, Kidokoro A, Fukunaga M, Momose F, Fuse S, Nagakari K: [Comparison between continuous intravenous and oral administration of 5-FU with LV]. Gan To Kagaku Ryoho. 1999 Apr;26(5):631-5. Tumor volume, thymidylate synthase inhibition rate (TSIR) and body weight were measured at the end of infusion. |
1(0,0,0,1) | Details |