| Name | c fos |
|---|---|
| Synonyms | Cellular oncogene fos; FBJ murine osteosarcoma viral (v fos) oncogene homolog; FOS; G0/G1 switch regulatory protein 7; G0S7; Oncogene FOS; Proto oncogene protein c fos; c Fos… |
| Name | IBA |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9149901 | Kameda T, Watanabe H, Iba H: C-Jun and JunD suppress maturation of chondrocytes. . Cell Growth Differ. 1997 May;8(5):495-503. All the known components of chicken AP-1 (c-Fos, Fra-2, c-Jun, and JunD) were detected in both cell types, but the expression level of c-Jun was much higher in LS cells, which are rich in less mature chondrocytes than US cells. |
1(0,0,0,1) | Details |
| 9569029 | Matsumoto K, Saitoh K, Koike C, Narita T, Yasugi S, Iba H: Differential expression of fos and jun family members in the developing chicken gastrointestinal tract. Oncogene. 1998 Mar 26;16(12):1611-6. Expression of c-jun and c-fos was detectable in both mesenchyme and epithelium through the whole tract. |
1(0,0,0,1) | Details |
| 11108151 | Matsubara H, Moriguchi Y, Mori Y, Masaki H, Tsutsumi Y, Shibasaki Y, Uchiyama-Tanaka Y, Fujiyama S, Koyama Y, Nose-Fujiyama A, Iba S, Tateishi E, Iwasaka T: Transactivation of EGF receptor induced by angiotensin II regulates fibronectin and TGF-beta gene expression via transcriptional and post-transcriptional mechanisms. Mol Cell Biochem. 2000 Sep;212(1-2):187-201. We concluded that Ang II-induced expression of fibronectin and TGF-beta is mediated by downstream signaling of EGF-R transactivated by Ca2+-dependent kinase, and that Ang II-induced fibronectin mRNA expression is regulated by two different mechanisms; transcriptional control by binding of c-fos/c-jun complex to the AP-1 site, and post-transcriptional control by mRNA stabilization due to autocrine and/or paracrine effects of TGF-beta. |
1(0,0,0,1) | Details |
| 7936655 | Foletta VC, Sonobe MH, Suzuki T, Endo T, Iba H, Cohen DR: Cloning and characterisation of the mouse fra-2 gene. Oncogene. 1994 Nov;9(11):3305-11. Transcription factor AP-1 is comprised of multiple protein complexes that include members of a family of genes related to the proto-oncogene c-fos. |
1(0,0,0,1) | Details |
| 2514403 | Yoshida T, Shindo Y, Ohta K, Iba H: Identification of a small region of the v-fos gene product that is sufficient for transforming potential and growth-stimulating activity. Oncogene Res. 1989;5(2):79-89. The central region that is sufficient for these activities includes the evolutionarily highly conserved region among human, mouse and chicken c-fos proteins. |
1(0,0,0,1) | Details |
| 11566906 | Shibasaki Y, Matsubara H, Nozawa Y, Mori Y, Masaki H, Kosaki A, Tsutsumi Y, Uchiyama Y, Fujiyama S, Nose A, Iba O, Tateishi E, Hasegawa T, Horiuchi M, Nahmias C, Iwasaka T: Angiotensin II type 2 receptor inhibits epidermal growth factor receptor transactivation by increasing association of SHP-1 phosphatase. Hypertension. 2001 Sep;38(3):367-72. AT (1)-mediated c-fos mRNA accumulation was attenuated by 48% by AT (2) stimulation. |
1(0,0,0,1) | Details |
| 11053448 | Ito T, Yamauchi M, Nishina M, Yamamichi N, Mizutani T, Ui M, Murakami M, Iba H: Identification of SWI.SNF complex subunit BAF60a as a determinant of the transactivation potential of Fos/Jun dimers. J Biol Chem. 2001 Jan 26;276(4):2852-7. Epub 2000 Oct 26. BAF60a binds to a specific subset of Fos/Jun heterodimers using two different interfaces for c-Fos and c-Jun, respectively. |
1(0,0,0,1) | Details |
| 1899576 | Yoshida T, Sato H, Iba H: Transcription of fra-2 mRNA and phosphorylation of Fra-2 protein are stimulated by serum. Biochem Biophys Res Commun. 1991 Jan 31;174(2):934-9. Compared with c-fos mRNA, expression of these fra-2 mRNAs was significantly prolonged, in good agreement with the previous analysis on the synthetic rate of Fos and Fra-2 proteins. |
1(0,0,0,1) | Details |
| 9500440 | Kameda T, Iba H: Suppression of cellular transformation by glucocorticoid receptor mutants. Cancer Res. 1998 Mar 1;58(5):867-70. When these GR mutants were expressed in chicken embryonic fibroblasts by retroviral vectors, they translocated into the nucleus without addition of glucocorticoid to the culture medium, and they suppressed cellular transformation caused by v-src and c-Ha-ras, as well as by c-fos and c-jun. |
1(0,0,0,1) | Details |
| 3316710 | Fujiwara KT, Ashida K, Nishina H, Iba H, Miyajima N, Nishizawa M, Kawai S: The chicken c-fos gene: cloning and nucleotide sequence analysis. J Virol. 1987 Dec;61(12):4012-8. |
6(0,0,0,6) | Details |
| 1945831 | Suzuki T, Okuno H, Yoshida T, Endo T, Nishina H, Iba H: Difference in transcriptional regulatory function between c-Fos and Fra-2. . Nucleic Acids Res. 1991 Oct 25;19(20):5537-42. |
6(0,0,0,6) | Details |
| 2110368 | Nishina H, Sato H, Suzuki T, Sato M, Iba H: Isolation and characterization of fra-2, an additional member of the fos gene family. Proc Natl Acad Sci U S A. 1990 May;87(9):3619-23. Antiserum raised against a Fos peptide (amino acids -127 to Arg-140 of chicken c-Fos) recognizes a 46-kDa Fos-related protein in cell lysates of growth-stimulated chicken embryo fibroblasts. |
5(0,0,0,5) | Details |
| 2851123 | Iba H, Shindo Y, Nishina H, Yoshida T: Transforming potential and growth stimulating activity of the v-fos and c-fos genes carried by avian retrovirus vectors. Oncogene Res. 1988;2(2):121-33. |
4(0,0,0,4) | Details |
| 14737107 | Joo A, Aburatani H, Morii E, Iba H, Yoshimura A: STAT3 and MITF cooperatively induce cellular transformation through upregulation of c-fos expression. Oncogene. 2004 Jan 22;23(3):726-34. |
4(0,0,0,4) | Details |
| 7862446 | Sonobe MH, Yoshida T, Murakami M, Kameda T, Iba H: fra-2 promoter can respond to serum-stimulation through AP-1 complexes. . Oncogene. 1995 Feb 16;10(4):689-96. This induction is delayed and prolonged compared to that of c-fos. |
4(0,0,0,4) | Details |
| 7687344 | Yoshida T, Suzuki T, Sato H, Nishina H, Iba H: Analysis of fra-2 gene expression. Nucleic Acids Res. 1993 Jun 11;21(11):2715-21. Like c-fos, fra-2 was inducible by phorbol ester, cAMP and ionophore, as well as serum. |
3(0,0,0,3) | Details |
| 9108093 | Watanabe H, Saitoh K, Kameda T, Murakami M, Niikura Y, Okazaki S, Morishita Y, Mori S, Yokouchi Y, Kuroiwa A, Iba H: Chondrocytes as a specific target of ectopic Fos expression in early development. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3994-9. The Finkel-Biskis-Jinkins murine sarcoma virus, which carries v-fos, induces osteosarcomas, whereas high-level expression of exogenous c-fos in transgenic and chimeric mice leads to postnatal development of osteogenic and chondrogenic tumors, respectively. |
2(0,0,0,2) | Details |
| 8415709 | Kameda T, Akahori A, Sonobe MH, Suzuki T, Endo T, Iba H: JunD mutants with spontaneously acquired transforming potential have enhanced transactivating activity in combination with Fra-2. Proc Natl Acad Sci U S A. 1993 Oct 15;90(20):9369-73. Compared with the wild-type JunD, none of them showed enhanced transactivating activity in the forms of homodimers or of heterodimers with c-Fos or Fra-1. |
1(0,0,0,1) | Details |