Name | Mu opioid receptor |
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Synonyms | MOR 1; MOR1; Mu opiate receptor; Mu opioid receptor; Mu type opioid receptor; OPRM; OPRM 1; OPRM1… |
Name | IBA |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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10602337 | Connor M, Borgland SL, Christie MJ: Continued morphine modulation of calcium channel currents in acutely isolated locus coeruleus neurons from morphine-dependent rats. Br J Pharmacol. 1999 Dec;128(7):1561-9. In LC neurons maintained in 5 microM morphine, co-superfusion of naloxone (1 microM) or the mu-opioid receptor antagonist CTAP (D- -Cys-Tyr-D-Trp-Arg- -Pen- -NH2 1 microM) with morphine resulted in a significant increase in the amplitude of IBa. |
31(0,1,1,1) | Details |
9824718 | Soldo BL, Moises HC: mu-opioid receptor activation inhibits N- and P-type Ca2+ channel currents in magnocellular neurones of the rat supraoptic nucleus. J Physiol. 1998 Dec 15;513 ( Pt 3):787-804. The mu-opioid receptor selective agonist, DAMGO, suppressed HVA IBa (in 64/71 neurones) in a naloxone-reversible and concentration-dependent manner (EC50 = 170 nM, Emax = 19.5 %). |
83(1,1,1,3) | Details |
10323586 | Connor M, Schuller A, Pintar JE, Christie MJ: Mu-opioid receptor modulation of calcium channel current in periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR-1. Br J Pharmacol. 1999 Apr;126(7):1553-8. The actions of opioid receptor agonists on the calcium channel currents (IBa) of acutely dissociated periaqueductal grey (PAG) neurons from C57B16/J mice and mutant mice lacking the first exon of the mu-opioid receptor (MOR-1) were examined using whole cell patch clamp techniques. |
32(0,1,1,2) | Details |
9463438 | Adams DJ, Trequattrini C: Opioid receptor-mediated inhibition of omega-conotoxin GVIA-sensitive calcium channel currents in rat intracardiac neurons. J Neurophysiol. 1998 Feb;79(2):753-62. Half-maximal inhibition of Ba2+ current (IBa) amplitude was obtained with 270 nM Met-enkephalin or Leu-enkephalin. Taken together, these data suggest that enkephalin-induced inhibition of Ca2+ channels in rat intracardiac neurons is mediated primarily by the mu-opioid receptor type. |
2(0,0,0,2) | Details |