Protein Information

Name tissue type plasminogen activator
Synonyms Alteplase; Neonatal thrombolytic agent alpha form; PLAT; PLAT protein; Reteplase; T PA; TPA; TPA protein…

Compound Information

Name IBA
CAS

Reference List

PubMed Abstract RScore(About this table)
16482045 Dankovtseva EN, Zateishchikov DA, Sidorenko BA: [Polymorphism of Genes of Factors of Hemostasis in Patients With Early Development of Ischemic Heart Disease.]. Kardiologiia. 2006;45(1):56-65.

Information is presented on polymorphisms of tissue factor, coagulation factors VII, V, prothrombin, thrombomodulin, fibrinogen, thrombin activated fibrinolysis inhibitor, tissue plasminogen activator inhibitor, platelet membrane glycoproteines Ia, Iba, IIIa in patients with early development of IHD.
31(0,1,1,1) Details
1903823 Iba T, Shin T, Sonoda T, Rosales O, Sumpio BE: Stimulation of endothelial secretion of tissue-type plasminogen activator by repetitive stretch. J Surg Res. 1991 May;50(5):457-60.

2(0,0,0,2) Details
1285345 Iba T, Sumpio BE: Tissue plasminogen activator expression in endothelial cells exposed to cyclic strain in vitro. Cell Transplant. 1992;1(1):43-50.

2(0,0,0,2) Details
19152657 Iba K, Hatakeyama N, Kojima T, Murata M, Matsumura T, Wewer UM, Wada T, Sawada N, Yamashita T: Impaired cutaneous wound healing in mice lacking tetranectin. . Wound Repair Regen. 2009 Jan-Feb;17(1):108-12.


Tetranectin enhances plasminogen activation by a tissue-type plasminogen activator so that it has been suggested to play a role in tissue remodeling.
1(0,0,0,1) Details
1326680 Iba T, Mills I, Sumpio BE: Intracellular cyclic AMP levels in endothelial cells subjected to cyclic strain in vitro. J Surg Res. 1992 Jun;52(6):625-30.


In parallel experiments, tissue plasminogen activator (tPA) secretion was determined after 24 hr of cyclic strain in the absence or presence of forskolin or galanin.
1(0,0,0,1) Details
8696988 Kidokoro A, Iba T, Fukunaga M, Yagi Y: Alterations in coagulation and fibrinolysis during sepsis. . Shock. 1996 Mar;5(3):223-8.


Tissue plasminogen activator (t-PA), plasminogen activator inhibitor 1 (PAI-1), and thrombomodulin were also measured.
1(0,0,0,1) Details
19899982 Wang WY, Xu GZ, Tian J, Sprecher AJ: Inhibitory effect on LPS-induced retinal microglial activation of downregulation of t-PA expression by siRNA interference. Curr Eye Res. 2009 Jun;34(6):476-84.


PURPOSE: This study investigated the expression and release of tissue plasminogen activator (t-PA) in lipopolysaccharide (LPS)-induced retinal microglia activation.
1(0,0,0,1) Details