Protein Information

Name brains
Synonyms BPG dependent PGAM 1; Brain; CDABP0006; PGAM 1; PGAM B; PGAM1; PGAM1 protein; PGAMA…

Compound Information

Name IBA
CAS

Reference List

PubMed Abstract RScore(About this table)
18190912 He J, Crews FT: Increased MCP-1 and microglia in various regions of the human alcoholic brain. Exp Neurol. 2008 Apr;210(2):349-58. Epub 2007 Dec 3.


In the current study, human postmortem brains from moderate drinking controls and alcoholics obtained from the New South Wales Tissue Resource Center were used to study the cytokine, monocyte chemoattractant protein 1 (MCP-1,CCL2) and microglia markers in various brain regions.
4(0,0,0,4) Details
19070908 Kalm M, Lannering B, Bjork-Eriksson T, Blomgren K: Irradiation-induced loss of microglia in the young brain. . J Neuroimmunol. 2009 Jan 3;206(1-2):70-5. Epub 2008 Dec 13.


Here we have characterized the microglia response after a single dose of 8 Gy to the brains of postnatal day 9 or 21 rats.
1(0,0,0,1) Details
8389058 Yao Y, Zhu H, Yang YS, Bao YD: [A voltage-clamp study on voltage-gated calcium channels translated in Xenopus oocytes by rat brain mRNA]. Sheng Li Xue Bao. 1993 Feb;45(1):44-54.

The properties of the calcium channels were characterized by barium current (IBa) passed through the channels.
In comparison, the expression of voltage-activated barium current was hardly detectable in oocytes injected by mRNA extracted from brains of embryonic rats.
1(0,0,0,1) Details
2435866 Leonard JP, Nargeot J, Snutch TP, Davidson N, Lester HA: Ca channels induced in Xenopus oocytes by rat brain mRNA. J Neurosci. 1987 Mar;7(3):875-81.

RNA was isolated from brains of 16-d-old rats and poly (A) samples were injected into stage V and VI oocytes.
IBa in noninjected oocytes was often undetectable, but ranged up to 50 nA (22 +/- 4 nA, n = 21).
1(0,0,0,1) Details
20025929 Sakoori K, Murphy NP: Reduced degeneration of dopaminergic terminals and accentuated astrocyte activation by high dose methamphetamine administration in nociceptin receptor knock out mice. Neurosci Lett. 2010 Jan 29;469(3):309-13. Epub 2009 Dec 16.


Three days later, brains were immunohistochemically processed to visualize methamphetamine-induced loss of tyrosine hydroxylase (as a marker of damage to dopamine terminals), glial fibrillary acidic protein (GFAP, as a marker of astrocytes), and ionized calcium-binding adapter molecule 1 (lba-1, as a marker of microglia) in the striatum.
1(0,0,0,1) Details