Protein Information

Name C18
Synonyms B1; D1; BBS 9; BBS9; BBS9 GENE; Bardet Biedl syndrome 9 protein; C18; PTH responsive osteosarcoma B1 protein…

Compound Information

Name jasmonic acid
CAS

Reference List

PubMed Abstract RScore(About this table)
10549556 Weiler EW, Laudert D, Stelmach BA, Hennig P, Biesgen C, Kubigsteltig I: Octadecanoid and hexadecanoid signalling in plant defence. Novartis Found Symp. 1999;223:191-204.

Key to understanding octadecanoid biology are the C18-metabolite 12-oxophytodienoic acid (OPDA) and the C12-compound jasmonic acid which is biosynthetically derived from 12-oxophytodienoic acid.
82(1,1,1,2) Details
8194607 Weiler EW, Kutchan TM, Gorba T, Brodschelm W, Niesel U, Bublitz F: The Pseudomonas phytotoxin coronatine mimics octadecanoid signalling molecules of higher plants. FEBS Lett. 1994 May 23;345(1):9-13.

While coronafacic acid is similar in structure to jasmonic acid, we found coronatine to be a close structural analogue of the cyclic C18-precursor of jasmonic acid, 12-oxo-phytodienoic acid.
6(0,0,1,1) Details
12119169 Blee E: Impact of phyto-oxylipins in plant defense. Trends Plant Sci. 2002 Jul;7(7):315-22.

During the past decade, interest in this field was focused on the biosynthesis of jasmonic acid (one branch of C18 polyunsaturated fatty acid metabolism) and on its relationship to the other plant defense-signaling pathways.
6(0,0,1,1) Details
16189680 Kristl J, Veber M, Krajnicic B, Oresnik K, Slekovec M: Determination of jasmonic acid in Lemna minor (L.) by liquid chromatography with fluorescence detection. Anal Bioanal Chem. 2005 Nov;383(5):886-93. Epub 2005 Nov 5.

Derivatives of JA and dh-JA were separated with gradient elution on a C18 reversed-phase column using acetonitrile/water as a mobile phase and detected by a fluorescence detector at excitation and emission wavelengths of 254 and 412 nm, respectively.
1(0,0,0,1) Details
17428728 Gaquerel E, Herve C, Labriere C, Boyen C, Potin P, Salaun JP: Evidence for oxylipin synthesis and induction of a new polyunsaturated fatty acid hydroxylase activity in Chondrus crispus in response to methyljasmonate. Biochim Biophys Acta. 2007 May;1771(5):565-75. Epub 2007 Mar 2.


The marine red alga Chondrus crispus uses both oxygenated derivatives of C18 (octadecanoids) and C20 (eicosanoids) PUFAs as developmental or defense hormones.
1(0,0,0,1) Details
15722469 Li C, Schilmiller AL, Liu G, Lee GI, Jayanty S, Sageman C, Vrebalov J, Giovannoni JJ, Yagi K, Kobayashi Y, Howe GA: Role of beta-oxidation in jasmonate biosynthesis and systemic wound signaling in tomato. Plant Cell. 2005 Mar;17(3):971-86. Epub 2005 Feb 18.

Jasmonic acid (JA) is a lipid-derived signal that regulates plant defense responses to biotic stress.
Recombinant ACX1A exhibited a preference for C12 and C14 straight-chain acyl-CoAs and also was active in the metabolism of C18 cyclopentanoid-CoA precursors of JA.
1(0,0,0,1) Details
8130256 Gerwick WH: Structure and biosynthesis of marine algal oxylipins. Biochim Biophys Acta. 1994 Mar 24;1211(3):243-55.


In general, the red algae metabolize C20 acids via 12-lipoxygenase-initiated pathways, green algae metabolize C18 acids at C-9 and C-13, and brown algae metabolize both C18 and C20 acids, principally by lipoxygenases with n-6 specificity.
1(0,0,0,1) Details
16963437 Koo AJ, Chung HS, Kobayashi Y, Howe GA: Identification of a peroxisomal acyl-activating enzyme involved in the biosynthesis of jasmonic acid in Arabidopsis. J Biol Chem. 2006 Nov 3;281(44):33511-20. Epub 2006 Sep 8.

The C18 JA precursor 12-oxo-phytodienoic acid (OPDA) is converted in the peroxisome to 3-oxo-2-(2'-[Z]-pentenyl) cyclopentane-1-octanoic acid (OPC-8:0), which subsequently undergoes three rounds of beta-oxidation to yield JA.
1(0,0,0,1) Details