Protein Information

Name NDR1
Synonyms NDR; NDR 1; NDR1; NDR protein kinase; NDR1 protein kinase; Ndr Ser/Thr kinase like protein; Nuclear DBF2 related protein; Nuclear Dbf2 related kinase 1…

Compound Information

Name jasmonic acid
CAS

Reference List

PubMed Abstract RScore(About this table)
14666423 Zheng MS, Takahashi H, Miyazaki A, Hamamoto H, Shah J, Yamaguchi I, Kusano T: Up-regulation of Arabidopsis thaliana NHL10 in the hypersensitive response to Cucumber mosaic virus infection and in senescing leaves is controlled by signalling pathways that differ in salicylate involvement. Planta. 2004 Mar;218(5):740-50. Epub 2003 Dec 10.

The Arabidopsis thaliana (L.) Heyhn. genome contains 45 genes that show substantial sequence similarity to the tobacco ( Nicotiana tabacum L.) HIN1 (harpin-induced) gene and the Arabidopsis NDR1 (non-race-specific disease resistance) gene.
Studies using Arabidopsis mutants defective in salicylic acid (SA), ethylene and jasmonic acid signalling revealed that the senescence-associated expression of NHL10 is mediated by a pathway that involves SA but that NHL10 expression during CMV-induced HR and spermine treatment is totally independent of SA.
3(0,0,0,3) Details
10886772 McDowell JM, Cuzick A, Can C, Beynon J, Dangl JL, Holub EB: Downy mildew (Peronospora parasitica) resistance genes in Arabidopsis vary in functional requirements for NDR1, EDS1, NPR1 and salicylic acid accumulation. Plant J. 2000 Jun;22(6):523-9.

RPP7 resistance was also not compromised by mutations in EIN2, JAR1 or COI1 which affect ethylene or jasmonic acid signaling.
2(0,0,0,2) Details
16941900 Johansson A, Staal J, Dixelius C: Early responses in the Arabidopsis-Verticillium longisporum pathosystem are dependent on NDR1, JA- and ET-associated signals via cytosolic NPR1 and RFO1. Mol Plant Microbe Interact. 2006 Sep;19(9):958-69.

Analysis of mutants impaired in known pathogen response pathways revealed an enhanced susceptibility in ein2-1, ein4-1, ein6-1, esa1-1, and pad1-1, but not in other jasmonic acid (JA)-, ethylene (ET)-, or camalexin-deficient mutants, suggesting that V. longisporum resistance is regulated via a hitherto unknown JA- and ET-associated pathway.
2(0,0,0,2) Details
11439131 Yoshioka K, Kachroo P, Tsui F, Sharma SB, Shah J, Klessig DF: Environmentally sensitive, SA-dependent defense responses in the cpr22 mutant of Arabidopsis. Plant J. 2001 May;26(4):447-59.


A cross between cpr22 and ndr1-1 mutants revealed that enhanced resistance to P. parasitica is mediated by an NDR1-dependent pathway, while the other cpr22-induced defenses are not.
1(0,0,0,1) Details
19825557 Zhang Z, Lenk A, Andersson MX, Gjetting T, Pedersen C, Nielsen ME, Newman MA, Hou BH, Somerville SC, Thordal-Christensen H: A lesion-mimic syntaxin double mutant in Arabidopsis reveals novel complexity of pathogen defense signaling. Mol Plant. 2008 May;1(3):510-27. Epub 2008 Apr 15.


Mutant alleles of EDS1, NDR1, RAR1, and SGT1b also partially rescued the lesion-mimic phenotype, suggesting that mutating syntaxin genes stimulates TIR-NB-LRR and CC-NB-LRR-type resistances.
1(0,0,0,1) Details
16306139 Kachroo P, Venugopal SC, Navarre DA, Lapchyk L, Kachroo A: Role of salicylic acid and fatty acid desaturation pathways in ssi2-mediated signaling. Plant Physiol. 2005 Dec;139(4):1717-35. Epub 2005 Nov 23.

Our previous work with the Arabidopsis (Arabidopsis thaliana) ssi2/fab2 mutant and its suppressors demonstrated that a balance between glycerol-3-phosphate (G3P) and 18:1 levels is critical for the regulation of salicylic acid (SA)- and jasmonic acid-mediated defense signaling in the plant.
However, ssi2-triggered defects in the jasmonic acid pathway, morphology, and cell death phenotypes are independent of the EDS1, EDS5, PAD4, NDR1, SID2, FAD3, FAD4, FAD5, DGD1, FAD7, and FAD7 FAD8 genes.
1(0,0,0,1) Details
17163880 Lee J, Nam J, Park HC, Na G, Miura K, Jin JB, Yoo CY, Baek D, Kim DH, Jeong JC, Kim D, Lee SY, Salt DE, Mengiste T, Gong Q, Ma S, Bohnert HJ, Kwak SS, Bressan RA, Hasegawa PM, Yun DJ: Salicylic acid-mediated innate immunity in Arabidopsis is regulated by SIZ1 SUMO E3 ligase. Plant J. 2007 Jan;49(1):79-90. Epub 2006 Dec 6.


Jasmonic acid (JA)-induced PDF1.2 expression and susceptibility to Botrytis cinerea were unaltered in siz1 plants.
0(0,0,0,0) Details
15773856 Xiao S, Calis O, Patrick E, Zhang G, Charoenwattana P, Muskett P, Parker JE, Turner JG: The atypical resistance gene, RPW8, recruits components of basal defence for powdery mildew resistance in Arabidopsis. Plant J. 2005 Apr;42(1):95-110.


In contrast, NDR1, RAR1 and PBS3 that are required for function of certain NB-LRR R genes, and COI1 and EIN2 that operate, respectively, in the jasmonic acid and ethylene signalling pathways, do not contribute to RPW8.1 and RPW8.2-mediated resistance.
0(0,0,0,0) Details