Protein Information

Name CTR1
Synonyms CALCR; CTR 1; CTR1; CRT; CT R; CTR; Calcitonin receptor; Calcitonin receptor precursor…

Compound Information

Name jasmonic acid
CAS

Reference List

PubMed Abstract RScore(About this table)
18713391 Zhu Z, Guo H: Genetic basis of ethylene perception and signal transduction in Arabidopsis. J Integr Plant Biol. 2008 Jul;50(7):808-15.

Ethylene has been shown to also regulate many other hormones' signaling pathways including auxin, abscisic acid and jasmonic acid, implying the existence of complicated signaling networks in the growth, development and defense responses of various plants.
In the presence of ethylene treatment, all ethylene receptors are in an activated form, which can physically interact with CTR1 and consequently recruit CTR1 protein to endoplasmic reticulum membraneto activate it.
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15144381 Liu Y, Schiff M, Dinesh-Kumar SP: Involvement of MEK1 MAPKK, NTF6 MAPK, WRKY/MYB transcription factors, COI1 and CTR1 in N-mediated resistance to tobacco mosaic virus. Plant J. 2004 Jun;38(5):800-9.

In addition, suppression of jasmonic acid (JA) signaling component COI1 ortholog affected N function.
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15200642 Tuominen H, Overmyer K, Keinanen M, Kollist H, Kangasjarvi J: Mutual antagonism of ethylene and jasmonic acid regulates ozone-induced spreading cell death in Arabidopsis. Plant J. 2004 Jul;39(1):59-69.

Physiological experiments suggested that the target of JA is upstream of Constitutive Triple Response 1 (CTR1), but downstream of ET biosynthesis.
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18943839 Shoresh M, Yedidia I, Chet I: Involvement of Jasmonic Acid/Ethylene Signaling Pathway in the Systemic Resistance Induced in Cucumber by Trichoderma asperellum T203. Phytopathology. 2005 Jan;95(1):76-84.

Moreover, examination of local and systemic gene expression by real-time reverse transcription-polymerase chain reaction analysis revealed that T. asperellum (T203) modulates the expression of genes involved in the jasmonate/ethylene signaling pathways of ISR (Lox1, Pal1, ETR1, and CTR1) in cucumber plants.
1(0,0,0,1) Details
15784880 Stepanova AN, Alonso JM: Arabidopsis ethylene signaling pathway. Sci STKE. 2005 Mar 22;2005(276):cm4.

The coregulation of ERF1 by another plant hormone, jasmonic acid, illustrates how a transcriptional cascade could be utilized in a combinatorial fashion to generate a large diversity of responses using a limited number of input signals.
Derepression of EIN2 by ethylene upon disabling of the receptors and CTR1 leads to the activation of EIN3 and EIN3-like transcription factors.
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11114160 Frye CA, Tang D, Innes RW: Negative regulation of defense responses in plants by a conserved MAPKK kinase. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):373-8.


In contrast, the ein2 mutation did not suppress edr1-mediated resistance and associated phenotypes, indicating that ethylene and jasmonic acid-induced responses are not required for edr1 resistance.
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