Protein Information

Name alkaline phosphatases
Synonyms ALPL; ALPL protein; ALPL protein variant; AP TNAP; Alkalin phosphatase; Alkaline phosphatase; HOPS; Liver/bone/kidney isozyme…

Compound Information

Name phosphorus
CAS phosphorus

Reference List

PubMed Abstract RScore(About this table)
19434343 Yilmaz A, Nur N, Turgut B: Leptin and bone mineral density in haemodialysis patients. Ann Acad Med Singapore. 2009 Apr;38(4):374-4.

BMD at the distal radius correlated positively with bone alkaline phosphatase (BAP) (r = 0.503, P = 0.005) in male patients and correlated positively with phosphorus (r = 0.343, P = 0.02) in female patients.
6(0,0,1,1) Details
20301083 Lomonte C, Derosa C, Vernaglione L, Casucci F, Losurdo N, Libutti P, Teutonico A, Basile C: Serum parathyroid hormone and phosphate influence the levels of circulating CD34+ cells in uremia. J Nephrol. 2010 Mar 18. pii: 8A13134E-146D-475D-8FDC-866EB2E16427.

Serum PTH, calcium (Ca), phosphorus (P), alkaline phosphatases (ALP), urea nitrogen, albumin and hemoglobin were measured.
6(0,0,1,1) Details
20175051 Lomonte C, Casucci F, Libutti P, Losurdo N, Teutonico A, Basile C: Vitamin D treatment in hemodialysis patients with low serum levels of parathyroid hormone: which is the best choice?. J Nephrol. 2010 Mar-Apr;23(2):210-5.

Results: Group A showed a statistically significant increase in the serum levels of calcium corrected for serum albumin (cCa), phosphorus (P), total alkaline phosphatases (ALP), PTH and 25 (OH) D.
6(0,0,1,1) Details
19926862 Luo H, Benner R, Long RA, Hu J: Subcellular localization of marine bacterial alkaline phosphatases. . Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21219-23. Epub 2009 Nov 19.

The unexpectedly high abundance of cytoplasmic APases suggests that the transport and intracellular hydrolysis of small organophosphate molecules is an important mechanism for bacterial acquisition of phosphorus (P) in the surface ocean.
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19555381 Orchard ED, Webb EA, Dyhrman ST: Molecular analysis of the phosphorus starvation response in Trichodesmium spp. Environ Microbiol. 2009 Sep;11(9):2400-11. Epub 2009 Jun 25.

To better understand how this genus responds to P starvation we examined four genes involved in P acquisition: two copies of a high-affinity phosphate binding protein (pstS and sphX) and two putative alkaline phosphatases (phoA and phoX).
1(0,0,0,1) Details
20093006 Xie C, Lu R, Huang Y, Wang Q, Xu X: Effects of ions and phosphates on alkaline phosphatase activity in aerobic activated sludge system. Bioresour Technol. 2010 May;101(10):3394-9. Epub 2010 Jan 25.

The influence of metal ions, anions, ortho-phosphate, polyphosphate and organic phosphorus on the activity and kinetics of alkaline phosphatase in aerobic activated sludge taken from a local municipal wastewater treatment plant was investigated.
V (max)/K (m) ratio is a good indicator for the catalytic efficiency of alkaline phosphatases in wastewater.
1(0,0,0,1) Details
19967658 Ferreira A, Saraiva M, Behets G, Macedo A, Galvao M, D'Haese P, Drueke TB: Evaluation of bone remodeling in hemodialysis patients: serum biochemistry, circulating cytokines and bone histomorphometry. J Nephrol. 2009 Nov-Dec;22(6):783-93.

Serum levels of intact parathyroid hormone (iPTH; 1-84), total alkaline phosphatases (tAP), calcium, phosphate and aluminum (Al) were measured.
Serum calcium and phosphorus, however, did not differ (p=NS).
1(0,0,0,1) Details
19548062 Yano S, Suzuki K, Sumi M, Tokumoto A, Shigeno K, Himeno Y, Sugimoto T: Bone metabolism after cinacalcet administration in patients with secondary hyperparathyroidism. J Bone Miner Metab. 2010;28(1):49-54. Epub 2009 Jun 23.


Serum bone alkaline phosphatase, a marker of bone formation, was increased at week 2 compared with the basal level.
1(0,0,0,1) Details
19819110 Portela ML, Monico A, Barahona A, Dupraz H, Sol Gonzales-Chaves MM, Zeni SN: Comparative 25-OH-vitamin D level in institutionalized women older than 65 years from two cities in Spain and Argentina having a similar solar radiation index. Nutrition. 2010 Mar;26(3):283-9. Epub 2009 Oct 9.

Conversely, bone alkaline phosphatase increased significantly only when the PTH concentration duplicated the reference range.
OBJECTIVE: The present study evaluated and compared vitamin D nutritional status and calcium-phosphorus metabolism in institutionalized women > 65 y from two cities that have a similar sun irradiation index (heliophany).
1(0,0,0,1) Details
19337166 Tantawy AA, El Kholy M, Moustafa T, Elsedfy HH: Bone mineral density and calcium metabolism in adolescents with beta-thalassemia major. Pediatr Endocrinol Rev. 2008 Oct;6 Suppl 1:132-5.

Bone mineral density (BMD) at both the lumbar spine and femoral neck was measured in 40 adolescents with beta thalassemia major (TM) by DXA scanning and correlated to biochemical parameters including calcium, phosphorus, alkaline phosphatase, bone alkaline phosphatase, intact parathyroid hormone and 25-OH vitamin D as well as vitamin D receptor (VDR) gene polymorphisms at exon 2 (Fok1).
32(0,1,1,2) Details