Protein Information

Name FPGS
Synonyms FPGS; FPGS protein; Folate polyglutamate synthetase; Folylpoly gamma glutamate synthetase; Folylpolyglutamate synthase; Folylpolyglutamate synthetase cytosolic isoform; Folylpolyglutamate synthetase mitochondrial isoform; Folylpolyglutamyl synthetase…

Compound Information

Name phosphorus
CAS phosphorus

Reference List

PubMed Abstract RScore(About this table)
19563773 McGuire JJ, Bartley DM, Tomsho JW, Haile WH, Coward JK: Inhibition of human folylpolyglutamate synthetase by diastereomeric phosphinic acid mimics of the tetrahedral intermediate. Arch Biochem Biophys. 2009 Aug 15;488(2):140-5. Epub 2009 Jun 27.

Phosphorus-containing pseudopeptides, racemic at the C-terminal alpha-carbon, are potent mechanism-based inhibitors of folylpolyglutamate synthetase (FPGS).
85(1,1,1,5) Details