Protein Information

Name tumor necrosis factor alpha
Synonyms Cachectin; DIF; TNF; TNF alpha; TNF a; TNFA; TNFSF 2; TNFSF2…

Compound Information

Name phosphorus
CAS phosphorus

Reference List

PubMed Abstract RScore(About this table)
19621176 Kunstmann S, Vukusich A, Michea L, Varela C, Allende I, Bravo S, Gainza D, Sepulveda D, Marusic E, Figueroa F: [Cardiovascular assessment of non diabetic patients on hemodialysis] . Rev Med Chil. 2009 Mar;137(3):351-60. Epub 2009 Jun 15.

No correlations were found between ventricular hypertrophy and dialysis lapse, packed red cell volume, calcium phosphorus product, parathormone levels or median arterial pressure.
In 26 patients, interleukin 6, tumor necrosis factor alpha, and intercellular adhesion molecule (ICAM-1) were also measured.
2(0,0,0,2) Details
19652016 Smith AM, Rahman FZ, Hayee B, Graham SJ, Marks DJ, Sewell GW, Palmer CD, Wilde J, Foxwell BM, Gloger IS, Sweeting T, Marsh M, Walker AP, Bloom SL, Segal AW: Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease. J Exp Med. 2009 Aug 31;206(9):1883-97. Epub 2009 Aug 3.


Despite normal levels and stability of cytokine messenger RNA, intracellular levels of tumor necrosis factor (TNF) were abnormally low in CD macrophages.
1(0,0,0,1) Details
19389948 Loiselle MC, Ster C, Talbot BG, Zhao X, Wagner GF, Boisclair YR, Lacasse P: Impact of postpartum milking frequency on the immune system and the blood metabolite concentration of dairy cows. J Dairy Sci. 2009 May;92(5):1900-12.

Blood concentrations of nonesterified fatty acids (NEFA), beta-hydroxybutyric acid (BHBA), calcium, bilirubin, urea, phosphorus, glucose, leptin, stanniocalcin-1, and 17beta-estradiol were determined in samples collected from 5 wk before scheduled calving to 5 wk after calving.
Peripheral blood mononuclear cells (PBMC) were isolated to evaluate lymphocyte proliferation and cytokine production (tumor necrosis factor-alpha, IL-4, and interferon-gamma).
1(0,0,0,1) Details
20059427 Lutfioglu M, Sakallioglu U, Sakallioglu EE, Diraman E, Ciftci G, Tutkun F: Dietary-induced hyperparathyroidism affects serum and gingival proinflammatory cytokine levels in rats. J Periodontol. 2010 Jan;81(1):150-7.

METHODS: Twenty-four Sprague-Dawley rats were used in the study. dHPT was induced in 12 rats by calcium/phosphorus imbalance, and 12 rats were fed a standard diet (SD).
Interleukin (IL)-1beta and tumor necrosis factor-alpha (TNF-alpha) levels were measured by enzyme-linked immunosorbent assay to evaluate the proinflammatory cytokine profiles.
1(0,0,0,1) Details
19967658 Ferreira A, Saraiva M, Behets G, Macedo A, Galvao M, D'Haese P, Drueke TB: Evaluation of bone remodeling in hemodialysis patients: serum biochemistry, circulating cytokines and bone histomorphometry. J Nephrol. 2009 Nov-Dec;22(6):783-93.

Circulating IL-1beta, IL-6, IL-8, IL-10, IL-12p70 and tumor necrosis factor-alpha (TNF-alpha) were simultaneously quantified by flow cytometric immunoassay.
Serum calcium and phosphorus, however, did not differ (p=NS).
1(0,0,0,1) Details
19827189 Berezhnova IA, Korshunov GV: [Plasma lipids and interleukins in geriatric patients with ischemic heart disease]. Klin Lab Diagn. 2009 Aug;(8):3-6.

The serum levels of total cholesterol, triglycerides, high-density lipoproteins, low-density lipoproteins, apoA- and apoB-lipoproteins, calcium, phosphorus, alkaline phosphatase, etc. were measured on a Vitalab Flexor E. biochemical analyzer.
The increased levels of interleukin (IL)-1 beta and IL-6 suggest that there is an inflammatory reaction whereas those of tumor necrosis factor-alpha may be indicative of the body's autoimmune readiness.
1(0,0,0,1) Details
19427183 Kong CS, Kim JA, Eom TK, Kim SK: Phosphorylated glucosamine inhibits adipogenesis in 3T3-L1 adipocytes. . J Nutr Biochem. 2009 May 6.

Phosphorylated glucosamine (glucosamine-6-phosphate, PGlc) was synthesized using methanesulfonic acid, phosphorus pentoxide (P (2) O (5)), NH (2) NH (2) and DMF.
According to the lipolytic response, PGlc up-regulated hormone-sensitive lipase mRNA expression and suppressed the expression levels of tumor necrosis factor-alpha mRNA compared with fully differentiated adipose tissue.
1(0,0,0,1) Details
19504563 Cobanoglu N, Atasoy H, Ozcelik U, Yalcin E, Dogru D, Kiper N, Gocmen A: Relation of bone mineral density with clinical and laboratory parameters in pre-pubertal children with cystic fibrosis. Pediatr Pulmonol. 2009 Jul;44(7):706-12.

After anthropometric measurements, BMD, serum calcium, phosphorus, total alkaline phosphatase (ALP), 25-hydroxy vitamin D (25-OHD), parathyroid hormone, osteocalcin, tumor necrosis factor (TNF)-alpha, soluble TNF-alpha receptor 2 (sTNFR2), and soluble IL-2 receptor (sIL-2R) levels, and urinary calcium and hydroxyproline excretions were assessed.
31(0,1,1,1) Details
19690405 Hasuike Y, Nonoguchi H, Ito K, Naka M, Kitamura R, Nanami M, Tokuyama M, Kida A, Otaki Y, Kuragano T, Nakanishi T: Interleukin-6 is a predictor of mortality in stable hemodialysis patients. Am J Nephrol. 2009;30(4):389-98. Epub 2009 Aug 19.

In stepwise multiple regression analyses, age, phosphorus and high-sensitivity C-reactive protein were independent predictors of IL-6 (R (2) = 0.466, p < 0.0001).
Baseline cross-sectional analysis of the relationship between inflammatory markers [interleukin-6 (IL-6), tumor necrosis factor-alpha and high-sensitivity C-reactive protein] and other factors, along with a survival analysis for death, were performed.
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