Protein Information

Name complex I
Synonyms 39kD; CI 39kD; Complex I; Complex I 39kD; NADH dehydrogenase (ubiquinone) Fe S protein 2 like; NADH ubiquinone oxidoreductase 39 kDa subunit mitochondrial; NADH ubiquinone oxidoreductase 39 kDa subunit; NDUFA 9…

Compound Information

Name phosphorus
CAS phosphorus

Reference List

PubMed Abstract RScore(About this table)
19505095 Piro NA, Cummins CC: An unusual P-P double bond formed via phospha-Wittig transformation of a terminal PO complex. J Am Chem Soc. 2009 Jul 1;131(25):8764-5.

The terminal phosphorus monoxide complex (OP) Mo (N [(t) Bu] Ar)(3), 1 (Ar = 3,5-Me (2) C (6) H (3)), undergoes an O-for-PSiR (3) metathesis reaction with the niobium phosphinidene complex (i) Pr (3) SiPNb (N [CH (2)(t) Bu] Ar)(3), 2, to generate the oxoniobium complex ONb (N [CH (2)(t) Bu] Ar)(3), 3, and the diphosphenido complex (i) Pr (3) SiPPMo (N [(t) Bu] Ar)(3), 4.
81(1,1,1,1) Details
19351177 Aponte AM, Phillips D, Hopper RK, Johnson DT, Harris RA, Blinova K, Boja ES, French S, Balaban RS: Use of (32) P to study dynamics of the mitochondrial phosphoproteome. J Proteome Res. 2009 Jun;8(6):2679-95.


These complexes were isolated by immunocapture, after (32) P labeling in the intact mitochondria, and revealed (32) P-incorporation for the alpha, beta, gamma, OSCP, and d subunits in Complex V and the 75, 51, 42, 23, and 13a kDa subunits in Complex I.
1(0,0,0,1) Details
19961238 Shinzawa-Itoh K, Seiyama J, Terada H, Nakatsubo R, Naoki K, Nakashima Y, Yoshikawa S: Bovine heart NADH-ubiquinone oxidoreductase contains one molecule of ubiquinone with ten isoprene units as one of the cofactors. Biochemistry. 2010 Jan 26;49(3):487-92.

NADH-ubiquinone oxidoreductase (Complex I) is located at the entrance of the mitochondrial electron transfer chain and transfers electrons from NADH to ubiquinone with 10 isoprene units (Q (10)) coupled with proton pumping.
An improved purification method including solubilization of mitochondrial membrane with deoxycholate followed by sucrose gradient centrifugation and anion-exchange column chromatography provided reproducibly a heme-free preparation containing 1 Q (10), 70 phosphorus atoms of phospholipids, 1 zinc ion, 1 FMN, 30 inorganic sulfur ions, and 30 iron atoms as the intrinsic constituents.
4(0,0,0,4) Details