Protein Information

Name Pit 1
Synonyms GLVR 1; PIT1; Pit 1; GLVR1; Gibbon ape leukemia virus receptor 1; Leukemia virus receptor 1 homolog; Phosphate transporter 1; SLC20A1…

Compound Information

Name phosphorus
CAS phosphorus

Reference List

PubMed Abstract RScore(About this table)
19546357 Zhou YB, Jin SJ, Cai Y, Teng X, Chen L, Tang CS, Qi YF: Lanthanum acetate inhibits vascular calcification induced by vitamin D3 plus nicotine in rats. Exp Biol Med. 2009 Aug;234(8):908-17. Epub 2009 Jun 22.

Lanthanum acetate at 750 mg/kg/day was more effective than 375 mg/kg/day in lessening vascular calcification by significantly reducing plasma phosphorus level, calcium x phosphorus product and ALP activity, by 30.3%, 28.6%, and 68.6%, respectively; reducing aortic phosphorus and calcium contents and ALP activity, by 48%, 53.1%, and 63.5% (all P < 0.01), respectively; reducing aortic mRNA level of OPN and Pit-1, by 55.8% (P < 0.01) and 38.8% (P < 0.05) and protein level of OPN and Pit-1, by 37.2% and 27.2% (both P < 0.01), respectively; and increasing carboxylated matrix Gla-protein (MGP) protein expression by 33.7% (P < 0.05), as compared with rats treated with vitamin D3 and nicotine alone.
87(1,1,2,2) Details
19329792 Koleganova N, Piecha G, Ritz E, Schirmacher P, Muller A, Meyer HP, Gross ML: Arterial calcification in patients with chronic kidney disease. . Nephrol Dial Transplant. 2009 Aug;24(8):2488-96. Epub 2009 Mar 27.


Calcium and phosphorus content in the aorta was quantitated using x-ray analysis.
0(0,0,0,0) Details
19675183 Giral H, Caldas Y, Sutherland E, Wilson P, Breusegem S, Barry N, Blaine J, Jiang T, Wang XX, Levi M: Regulation of rat intestinal Na-dependent phosphate transporters by dietary phosphate. Am J Physiol Renal Physiol. 2009 Nov;297(5):F1466-75. Epub 2009 Aug 12.


We have identified expression of the type III Na-P (i) cotransporter PiT-1 in the apical membrane of enterocytes.
2(0,0,0,2) Details