Protein Information

Name ERK2
Synonyms ERK; P40; ERK 2; ERK2; ERT 1; ERT1; Extracellular signal regulated kinase 2; MAP kinase 2…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
18694935 Mark JK, Aubin RA, Smith S, Hefford MA: Inhibition of mitogen-activated protein kinase phosphatase 3 activity by interdomain binding. J Biol Chem. 2008 Oct 17;283(42):28574-83. Epub 2008 Aug 11.


Mitogen-activated protein (MAP) kinase phosphatase 3 (MKP3) is a cytoplasmic dual specificity phosphatase that functions to attenuate signaling via dephosphorylation and subsequent deactivation of its substrate and allosteric regulator, extracellular signal-regulated protein kinase 2 (ERK2).
3(0,0,0,3) Details
17459723 Mark JK, Smith S, Hefford MA: Over-expression and refolding of MAP kinase phosphatase 3. Protein Expr Purif. 2007 Aug;54(2):253-60. Epub 2007 Mar 21.


MAP kinase phosphatase 3 (MKP3, also known as DUSP6 and PYST1) is involved in extracellular signal receptor kinase (ERK) regulation and functions as a specific phosphatase to the activated (phosphorylated) forms of ERK1 and ERK2.
2(0,0,0,2) Details