| Name | tumor necrosis factor alpha |
|---|---|
| Synonyms | Cachectin; DIF; TNF; TNF alpha; TNF a; TNFA; TNFSF 2; TNFSF2… |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20091890 | Hui C, Like W, Yan F, Tian X, Qiuyan W, Lifeng H: S-allyl- sulfoxide inhibits tumor necrosis factor-alpha induced monocyte adhesion and intercellular cell adhesion molecule-1 expression in human umbilical vein endothelial cells. Anat Rec. 2010 Mar;293(3):421-30. |
82(1,1,1,2) | Details |
| 19237170 | Minutoli L, Antonuccio P, Polito F, Bitto A, Squadrito F, Irrera N, Nicotina PA, Fazzari C, Montalto AS, Di Stefano V, Romeo C, Altavilla D: Peroxisome proliferator activated receptor beta/delta activation prevents extracellular regulated kinase 1/2 phosphorylation and protects the testis from ischemia and reperfusion injury. J Urol. 2009 Apr;181(4):1913-21. Epub 2009 Feb 23. We evaluated testicular extracellular signal regulated kinase, tumor necrosis factor-alpha and interleukin-6 by Western blot. |
3(0,0,0,3) | Details |
| 18596479 | Sivasankar M, Nofziger C, Blazer-Yost B: Cyclic adenosine monophosphate regulation of ion transport in porcine vocal fold mucosae. Laryngoscope. 2008 Aug;118(8):1511-7. Additionally, changes in cAMP concentrations following exposure to an inflammatory mediator, tumor necrosis factor-alpha (TNFalpha) were investigated. |
2(0,0,0,2) | Details |
| 18256785 | Yu HN, Lee YR, Noh EM, Lee KS, Song EK, Han MK, Lee YC, Yim CY, Park J, Kim BS, Lee SH, Lee SJ, Kim JS: Tumor necrosis factor-alpha enhances DMSO-induced differentiation of HL-60 cells through the activation of ERK/MAPK pathway. Int J Hematol. 2008 Mar;87(2):189-94. Epub 2008 Feb 8. |
2(0,0,0,2) | Details |
| 19241163 | Shirin H, Aeed H, Alin A, Matas Z, Kirchner M, Brazowski E, Goldiner I, Bruck R: Inhibition of immune-mediated concanavalin a-induced liver damage by free-radical scavengers. Dig Dis Sci. 2010 Feb;55(2):268-75. Epub 2009 Feb 25. Tumor necrosis factor alpha (TNFalpha) and interleukin-10 (IL-10) levels were assayed 2 h after Con A injection. |
2(0,0,0,2) | Details |
| 20118114 | Lu Y, Nie J, Liu X, Zheng Y, Guo SW: Trichostatin A, a histone deacetylase inhibitor, reduces lesion growth and hyperalgesia in experimentally induced endometriosis in mice. Hum Reprod. 2010 Apr;25(4):1014-25. Epub 2010 Jan 29. BACKGROUND: The aim of this study was to evaluate the effect of trichostatin A (TSA) in a mouse model of endometriosis on serum tumour necrosis factor alpha (TNFalpha) levels, hotplate latency, lesion size and immunoreactivity to Trpv1, Pkcepsilon and Pgp9.5. |
2(0,0,0,2) | Details |
| 17603938 | Pradeepkumar Singh L, Kundu P, Ganguly K, Mishra A, Swarnakar S: Novel role of in downregulation of matrix metalloproteinase-9 during protection of -induced acute gastric ulcer. Free Radic Biol Med. 2007 Jul 15;43(2):289-99. Epub 2007 Apr 29. Increased secretion of proMMP-9 was associated with increased expression of tumor necrosis factor-alpha and interleukin-6. |
1(0,0,0,1) | Details |
| 18645497 | Ito T, Omori K, Rawson J, Todorov I, Asari S, Kuroda A, Shintaku J, Itakura S, Ferreri K, Kandeel F, Mullen Y: Improvement of canine islet yield by donor pancreas infusion with a p38MAPK inhibitor. Transplantation. 2008 Jul 27;86(2):321-9. Tumor necrosis factor-alpha expression assessed by real-time reverse transcription polymerase chain reaction was significantly lower in the p38IH-treated group than controls. |
1(0,0,0,1) | Details |
| 19878061 | Akkok CA, Liseth K, Hervig T, Ryningen A, Bruserud O, Ersvaer E: Use of different DMSO concentrations for cryopreservation of autologous peripheral blood stem cell grafts does not have any major impact on levels of leukocyte- and platelet-derived soluble mediators. Cytotherapy. 2009;11(6):749-60. Low or undetectable levels of leukocyte-derived interleukin (IL)-6 and tumor necrosis factor (TNF)-alpha and CXCL8, high levels of platelet-derived CCL5 and CXCL4, and high levels of monocyte-derived soluble CD14 were measured independent of the DMSO concentration, except for slightly increased CXCL8 and decreased CXCL4 levels with 2% DMSO. |
1(0,0,0,1) | Details |
| 18827361 | Okemoto K, Hanada K, Nishijima M, Kawasaki K: The preparation of a lipidic endotoxin affects its biological activities. Biol Pharm Bull. 2008 Oct;31(10):1952-4. Macrophages stimulated with OL or lipid A sonically dissolved in saline released both interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha). |
1(0,0,0,1) | Details |
| 19551541 | Akkok CA, Liseth K, Hervig T, Ryningen A, Bruserud O, Ersvaer E: Use of different DMSO concentrations for cryopreservation of autologous peripheral blood stem cell grafts does not have any major impact on levels of leukocyte- and platelet-derived soluble mediators. Cytotherapy. 2009 Jun 23:1-12. Low or undetectable levels of leukocyte-derived intereukin (IL)-6 and tumor necrosis factor (TNF)-alpha and CXCL8, high levels of platelet-derived CCL5 and CXCL4, and high levels of monocyte-derived soluble CD14 were measured independent of the DMSO concentration, except for slightly increased CXCL8 and decreased CXCL4 levels with 2% DMSO. |
1(0,0,0,1) | Details |
| 19336900 | Kim YH, Kim DH, Lim H, Baek DY, Shin HK, Kim JK: The anti-inflammatory effects of on lipopolysaccharide-induced inflammatory responses in murine macrophages. Biol Pharm Bull. 2009 Apr;32(4):651-6. Furthermore, the levels of interleukin-6 and tumor necrosis factor-alpha were decreased by MSM treatment in cell culture supernatants. |
1(0,0,0,1) | Details |
| 18457866 | Saito M, Watanabe S: Differential modulation of lipopolysaccharide- and zymosan-induced hypophagia by dexamethasone treatment. Pharmacol Biochem Behav. 2008 Sep;90(3):428-33. Epub 2008 Apr 4. The attenuated response was associated with the suppression of the gene induction of proinflammatory cytokines (i.e., IL-1beta, IL-6 and TNFalpha) in the brain and liver. |
1(0,0,0,1) | Details |
| 17518680 | Lehle K, Hoenicka M, Jacobs VR, Schmid FX, Birnbaum DE: Identification and reduction of cryoinjury in endothelial cells: a first step toward establishing a cell bank for vascular tissue engineering. Tissue Eng. 2006 Dec;12(12):3439-47. However, the tumor necrosis factor-induced expression of adhesion molecules was significantly increased after long-term storage. |
1(0,0,0,1) | Details |
| 19474210 | Liu Y, Shi J, Lu J, Meng G, Zhu H, Hou Y, Yin Y, Zhao S, Ding B: Activation of peroxisome proliferator-activated receptor-gamma potentiates pro-inflammatory cytokine production, and and somatotropic changes of weaned pigs after Escherichia coli lipopolysaccharide challenge. Innate Immun. 2009 Jun;15(3):169-78. Rather, plasma levels of tumor necrosis factor-a (TNF-a) and interleukin-6 (IL-6), mRNA abundance of TNF-a in thymus, spleen, mesenteric lymph node and peripheral white blood cells, mRNA abundance of IL-6 in thymus, protein levels of TNF-a in spleen and mesenteric lymph node, and protein levels of IL-6 in spleen and mesenteric lymph node, were elevated beyond the levels in control pigs injected with LPS. |
1(0,0,0,1) | Details |
| 17549591 | Silva AR, Pinheiro AM, Souza CS, Freitas SR, Vasconcellos V, Freire SM, Velozo ES, Tardy M, El-Bacha RS, Costa MF, Costa SL: The rutin induces astrocyte and microglia activation and regulates TNF-alpha and NO release in primary glial cell cultures. Cell Biol Toxicol. 2008 Jan;24(1):75-86. Epub 2007 Jun 5. Enhanced TNFalpha release was observed in astrocyte primary cultures treated with 100 micromol/L rutin and in mixed primary cultures treated with 50 and 100 micromol/L, suggesting different sensitivity of both activated cell types. |
1(0,0,0,1) | Details |