Protein Information

Name bFGF
Synonyms BFGF; BHBGF 2; BHBGF2; Basic fibroblast growth factor; FGF; FGF2; FGFB; Fibroblast growth factor 2…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
18157297 Deolinda de Oliveira Pena J, Melo GB, Gomes JA, Haapalainen EF, Komagome CM, Santos NC, Souza Lima Filho AA, Rizzo LV: [Ultrastructural and growth factor analysis of amniotic membrane preserved by different methods for ocular surgery]. Arq Bras Oftalmol. 2007 Sep-Oct;70(5):756-62.


The cytokines and growth factors assessed were: TGF-beta (transforming growth factor beta); TGF-beta activ (activated transforming growth factor beta); EGF (epidermal growth factor); FGF-4 (fibroblast growth factor 4); bFGF (basic fibroblast growth factor); IL-4 (interleukin 4); PGE2 (prostaglandin E2); IL-10 (interleukin 10); KGF (keratinocyte growth factor); HGF (hepatocyte growth factor).
1(0,0,0,1) Details
19504477 Ohkubo T, Inagaki S, Min JZ, Kamiya D, Toyo'oka T: Rapid determination of oxidized methionine residues in recombinant human basic fibroblast growth factor by ultra-performance liquid chromatography and electrospray ionization quadrupole time-of-flight mass spectrometry with in-source collision-induced dissociation. Rapid Commun Mass Spectrom. 2009 Jul;23(13):2053-60.

Two methionine (Met) residues in the rhbFGF structure were oxidized to Met-sulfoxide (Met-O) in 0.03% H (2) O (2) at pH 2.0.
2(0,0,0,2) Details
20051678 Coradeghini R, Guida C, Scanarotti C, Sanguineti R, Bassi AM, Parodi A, Santi PL, Raposio E: A Comparative Study of Proliferation and Hepatic Differentiation of Human Adipose-Derived Stem Cells. Cells Tissues Organs. 2009 Dec 30.


In the first procedure, medium was supplemented with epidermal growth factor (EGF), basic fibroblast growth factor, hepatocyte growth factor (HGF) and nicotinamide; the second involved the addition of factors such as dexametasone, EGF, insulin-transferrin-sodium selenite, HGF, dimethyl sulfoxide and oncostatin.
1(0,0,0,1) Details
20091315 Roura S, Farre J, Hove-Madsen L, Prat-Vidal C, Soler-Botija C, Galvez-Monton C, Vilalta M, Bayes-Genis A: Exposure to cardiomyogenic stimuli fails to transdifferentiate human umbilical cord blood-derived mesenchymal stem cells. Basic Res Cardiol. 2010 May;105(3):419-30. Epub 2010 Jan 21.


The aim of this study was to direct UCBMSCs to the cardiac lineage by exposure to: (1) 5-azacytidine (AZ) or dimethyl sulfoxide (DMSO); (2) a combination of growth factors involved in early cardiomyogenesis (BMP-2 + bFGF + IGF-1); (3) the Wnt signaling activators lithium chloride (LiCl) and phorbol-12-myristate-13-acetate (PMA); and (4) direct contact with neonatal rat cardiomyocytes.
1(0,0,0,1) Details