| 2143106 |
Yoshida M, Shimokura M, Fujiwara Y, Fujisaki T, Akaji K, Kiso Y: Solution-phase synthesis of alpha-rat atrial natriuretic peptide (alpha-rANP). Chem Pharm Bull. 1990 Apr;38(4):1072-4.
alpha-Rat atrial natriuretic peptide (alpha-rANP) was synthesized by assembling five peptide fragments in solution, followed by HF-dimethylselenide-m-cresol deprotection and subsequent air-oxidation. Synthetic alpha-rANP exhibited more potent diuretic and natriuretic activity in rats than synthetic alpha-hANP. |
2(0,0,0,2) |