6454074 |
Zdzienicka M, Zielenska M, Trojanowska M, Szymczyk T, Bignami M, Carere A: Microbial short-term assays with thiram in vitro. Mutat Res. 1981 May;89(1):1-7. The fungicide thiram was assayed in the following tests in vitro, with and without metabolic activation: (1) prophage lambda induction of Escherichia coli K12; (2) repair test in Salmonella typhimurium (strains TA1538 and TA1978); (3) induction of gene mutations in Aspergillus nidulans (methA1 suppressor induction). Thiram was positive in the repair test and in the A. nidulans forward-mutation test (4-6 fold increase) in the absence of metabolic activation. A slight increase was observed in prophage lambda induction with thiram in the presence of the metabolic activation system. |
81(1,1,1,1) |