| 6578235 |
Mansson-Rahemtulla B, Pruitt KM, Tenovuo J, Le TM: A mouthrinse which optimizes in vivo generation of hypothiocyanite. J Dent Res. 1983 Oct;62(10):1062-6.
We report here the properties of a mouthrinse which enhances one of the natural defense factors in human saliva, the salivary peroxidase system. Concentrations of the antimicrobial agent, the hypothiocyanite (OSCN-) ion, can be increased in vivo to bacteriostatic levels by use of a mouthrinse which is 4 mM (0.014%) in hydrogen peroxide and 1 mM (0.0097%) in potassium thiocyanate at pH 5.5. The volume of the rinse, the H2O2 concentrations, and the pH were shown to be determinants of the concentration of OSCN- generated by the rinse. |
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