| 1424735 |
Saoudi A, Bellon B, de Kozak Y, Druet P: Adoptive transfer of experimental autoimmune uveoretinitis in HgCl2 injected rats. Curr Eye Res. 1992;11 Suppl:101-5.
We previously demonstrated that mercuric chloride (HgCl2) injected-(Lewis x Brown-Norway) F1 rats are protected against experimental autoimmune uveoretinitis (EAU) induced by active immunization with the retinal S-antigen (S-Ag). To better understand the mechanisms of the protection promoted by HgCl2, we studied the effect of HgCl2-induced autoimmune disease on transferred EAU. We demonstrate herein that HgCl2 has no effect on adoptively transferred EAU. Therefore, the HgCl2-induced autoimmune disease does not affect effector S-Ag specific T cells activated in vitro but acts at an earlier stage. |
6(0,0,1,1) |