| ID | 88 |
|---|---|
| Name | Acetylcholinesterase |
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| ID | 730 |
|---|---|
| Name | OCH |
| CAS | 2,3,4,4,5,5,6,6-octachloro-2-cyclohexen-1-one |
| PubMed | Abstract | RScore(About this table) |
|---|---|---|
| 15911280 | Kim TH, Kuca K, Jun D, Jung YS: Design and synthesis of new bis-pyridinium oxime reactivators for acetylcholinesterase inhibited by organophosphorous nerve agents. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2914-7. Epub 2005 Apr 21. New bis-pyridinium oxime reactivators connected with a CH (2) CH (2) OCH (2) CH (2) linker between two pyridinium rings were designed and synthesized. In the test of their potency to reactivate AChE inhibited by cyclosarin, the bis-pyridinium oxime 6b achieved reactivation potency higher than 10% at the lower concentration 10 (-4) M. |
2(0,0,0,2) |